葵子麝香

葵子麝香用途

【用途一】
用作香料及定香剂
【用途二】
该品是硝基麝香中香气最优雅的品种，具有琥珀气息的麝香香气，国内外均大量生产，在硝基香料中产量最多、用途最广的香料品种之一，主要用于配制各种香料与香精中作定香剂，特别适用于高级香水。在一些加香品中的用量为：肥皂0.03-0.2%，去垢剂0.003-0.02，香水0.2-2.0%，香脂和洗液0.01-0.07%。
【用途三】
该品是硝基麝香中香气最优雅的品种，具有琥珀气息的麝香香气，国内外均大量生产，在硝基香料中产量最多、用途最广的香料品种之一，主要用于配制各种香料与香精中作定香剂，特别适用于高级香水。

葵子麝香名称

[ CAS 号 ]:
83-66-9

[ 中文名 ]:
2,6-二硝基-3-甲氧基-4-叔丁基甲苯

[ 英文名 ]:
musk ambrette

[中文别名 ]:

[英文别名 ]:

5-tert-Butyl-1,3-dinitro-4-methoxy-2-methylbenzene
EINECS 201-493-7
2-tert-butyl-5-methyl-4,6-dinitroanisole
4-tert-Butyl-2,6-dinitro-3-methoxytoluene
6-tert-Butyl-3-methyl-2,4-dinitroanisol
syntheticmuskambrette
AMBRETTEMUSKRESIDUES
artificialmuskambrette
MOSCHUS-AMBRETTE
ambermust

葵子麝香物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
369.3±42.0 °C at 760 mmHg

[ 熔点 ]:
84-86°C

[ 分子式 ]:
C₁₂H₁₆N₂O₅

[ 分子量 ]:
268.266

[ 闪点 ]:
149.6±29.9 °C

[ 精确质量 ]:
268.105927

[ PSA ]:
100.87000

[ LogP ]:
3.71

[ 外观性状 ]:
淡黄色液体

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.542

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

葵子麝香MSDS

详细MSDS(安全技术说明书)

葵子麝香毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ8575000

CHEMICAL NAME :: Anisole, 6-t-butyl-3-methyl-2,4-dinitro-

CAS REGISTRY NUMBER :: 83-66-9

BEILSTEIN REFERENCE NO. :: 1889437

LAST UPDATED :: 199806

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C12-H16-N2-O5

MOLECULAR WEIGHT :: 268.30

WISWESSER LINE NOTATION :: WNR B1 DO1 CNW EX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 339 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory stimulation Skin and Appendages - hair

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10500 mg/kg/20W-I

TOXIC EFFECTS :: Behavioral - muscle weakness Musculoskeletal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6300 mg/kg/12W-C

TOXIC EFFECTS :: Brain and Coverings - demyelination Spinal Cord - demyelination Peripheral Nerve and Sensation - structural change in nerve or sheath

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6750 mg/kg/90D-I

TOXIC EFFECTS :: Spinal Cord - demyelination Peripheral Nerve and Sensation - structural change in nerve or sheath Related to Chronic Data - changes in testicular weight

MUTATION DATA

TEST SYSTEM :: Insect - Drosophila melanogaster

DOSE/DURATION :: 10 mmol/L

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,707,1983 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 65,477,1996 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 65,477,1996 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 65,477,1996 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83003 No. of Facilities: 260 (estimated) No. of Industries: 4 No. of Occupations: 20 No. of Employees: 23082 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83003 No. of Facilities: 1567 (estimated) No. of Industries: 11 No. of Occupations: 16 No. of Employees: 22736 (estimated) No. of Female Employees: 16492 (estimated)

葵子麝香安全信息

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
S26-S36/37/39

[ 危险品运输编码 ]:
2811

[ RTECS号 ]:
BZ8575000

[ 海关编码 ]:
2909309090

葵子麝香合成路线

详细合成路线

葵子麝香上下游产品

葵子麝香上游产品

葵子麝香下游产品

葵子麝香制备

【方法一】
以间甲酚为原料，用硫酸二甲酯甲基化，生成间甲酚甲醚，然后，间甲酚甲醚与异丁烯或叔丁醇反应生成叔丁基甲氧基甲苯，最后经硝化而得。

葵子麝香海关

[ 海关编码 ]: 2909309090

[ 中文概述 ]:
2909309090 其他芳香醚及其卤化衍生物、磺化、硝化衍生物（包括亚硝化衍生物）。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%