丙烯酸羟乙酯

丙烯酸羟乙酯用途

【用途一】
用于辐射固化体系中的活性稀释剂和交联剂，亦可作为树脂交联剂，塑料、橡胶改性剂
【用途二】
该品可与丙烯酸及酯、丙烯醛、丙烯腈、丙烯酰胺、甲基丙烯腈、氯乙烯、苯乙烯等很多单体进行共聚，所得产品可用于处理纤维，提高纤维的耐水性、耐溶剂性、防皱性和防水性；还用于制造性能优良的热固性涂料、合成橡胶，用作润滑油添加剂等。在粘合剂方面，与乙烯基单体共聚，可改进其粘接强度。在纸加工方面，用于制涂层用丙烯酸乳液，可提高其耐水性和强度。

丙烯酸羟乙酯名称

[ CAS 号 ]:
818-61-1

[ 中文名 ]:
丙烯酸羟乙酯

[ 英文名 ]:
2-Hydroxyethyl acrylate

[中文别名 ]:

[英文别名 ]:

2-Propenoic acid, 2-hydroxyethyl ester
bisomer2hea
2-Hydroxyethyl acryl
Hydroxyethyl acrylate
HEA
ethylene glycol monoacrylate
methanol,methyl acrylate
2-hydroxyethyl prop-2-enoate
acrylic acid 2-hydroxy-ethyl ester
4-acryloyloxyethyl alcohol

丙烯酸羟乙酯物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
196.2±23.0 °C at 760 mmHg

[ 熔点 ]:
-60 °C

[ 分子式 ]:
C₅H₈O₃

[ 分子量 ]:
116.115

[ 闪点 ]:
98.3±0.0 °C

[ 精确质量 ]:
116.047340

[ PSA ]:
46.53000

[ LogP ]:
-0.05

[ 外观性状 ]:
一种无色至淡黄色液体

[ 蒸汽密度 ]:
>1 (vs air)

[ 蒸汽压 ]:
0.1±0.8 mmHg at 25°C

[ 折射率 ]:
1.440

[ 储存条件 ]:
库房通风低温干燥

[ 水溶解性 ]:
soluble

丙烯酸羟乙酯MSDS

详细MSDS(安全技术说明书)

丙烯酸羟乙酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AT1750000

CHEMICAL NAME :: Acrylic acid, 2-hydroxyethyl ester

CAS REGISTRY NUMBER :: 818-61-1

BEILSTEIN REFERENCE NO. :: 0969853

LAST UPDATED :: 199801

DATA ITEMS CITED :: 20

MOLECULAR FORMULA :: C5-H8-O3

MOLECULAR WEIGHT :: 116.13

WISWESSER LINE NOTATION :: Q2OV1U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 650 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - convulsions or effect on seizure threshold Gastrointestinal - alteration in gastric secretion

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1010 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 38500 ug/m3/9W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Cardiac - EKG changes not diagnostic of specified effects Endocrine - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3900 mg/kg/13W-I

TOXIC EFFECTS :: Behavioral - ataxia Nutritional and Gross Metabolic - weight loss or decreased weight gain Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 38500 ug/m3/9W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Cardiac - EKG changes not diagnostic of specified effects Related to Chronic Data - death

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 15 mg/L

REFERENCE :: MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 4,381,1989 *** REVIEWS *** TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 11,141,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1326 No. of Facilities: 63 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 1845 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1326 No. of Facilities: 107 (estimated) No. of Industries: 4 No. of Occupations: 11 No. of Employees: 2370 (estimated) No. of Female Employees: 354 (estimated)

丙烯酸羟乙酯安全信息

[ 符号 ]:

GHS05, GHS06, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H311-H314-H317-H400

[ 警示性声明 ]:
P273-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P333 + P313

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
T:Toxic;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R20/22;R24;R34;R43;R50

[ 安全声明 (欧洲) ]:
S26-S36/39-S45-S61-S36/37/39

[ 危险品运输编码 ]:
UN 2927 6.1/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
AT1750000

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
2916129000

丙烯酸羟乙酯合成路线

详细合成路线

丙烯酸羟乙酯上下游产品

丙烯酸羟乙酯上游产品

丙烯酸羟乙酯下游产品

丙烯酸羟乙酯制备

1.丙烯酸与环氧乙烷在催化剂及阻聚剂存在下进行加成反应，生成丙烯酸-2-羟基乙基酯粗成品，经脱气、蒸馏得成品原料消耗定额：丙烯酸710kg/t、环氧乙烷485kg/t。

2.直接法　以丙烯酸和环氧乙烷为原料，在催化剂（三氯化钒、乙酸铬或丙烯酸铬）及对羟基苯甲醚阻聚剂存在下，经催化加成反应，最后蒸馏精制制得：

催化剂的制备：乙酸铬由含量为60%的乙酸铬水溶液蒸发浓缩得到。丙烯酸铬由如下反应制得：

将新解聚精制的丙烯酸置入100mL容量的圆筒形反应器中，加入催化剂和阻聚剂，开动电磁搅拌，通入N2吹扫，赶去空气。同时向反应器夹套通入恒温热水，使反应液达到设定温度。调节与反应器相连的回流冷凝管中冷却液的温度为－10～0℃（防止未反应的环氧乙烷逃逸）。关闭N2阀门，开启环氧乙烷钢瓶，液相或气相进料。当环氧乙烷加入量达到设定值后，关闭进料阀。环氧乙烷的进料速度根据反应过程中温度的变化来调整。进料完毕后，继续搅拌，于80℃保温一定的时间。

间接法　

丙烯酸羟乙酯海关

[ 海关编码 ]: 2916129000

[ 中文概述 ]:
2916129000 其他丙烯酸酯. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装

[ Summary ]:
2916129000 other esters of acrylic acid VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

丙烯酸羟乙酯文献

Micro-computed tomography image-based evaluation of 3D anisotropy degree of polymer scaffolds.

Comput. Methods Biomech. Biomed. Engin. 18(4) , 446-55, (2014)

Anisotropy is one of the most meaningful determinants of biomechanical behaviour. This study employs micro-computed tomography (μCT) and image techniques for analysing the anisotropy of regenerative m...

Neural tissue regeneration in experimental brain injury model with channeled scaffolds of acrylate copolymers.

Neurosci. Lett. 598 , 96-101, (2015)

The objective of the present study was to evaluate the biocompatibility and cell hosting ability of a copolymer scaffold based on ethyl acrylate (EA) and hydroxyl ethyl acrylate (HEA) in vivo after an...

Photopatterned oil-reservoir micromodels with tailored wetting properties.

Lab Chip 15 , 3047-55, (2015)

Micromodels with a simplified porous network that represents geological porous media have been used as experimental test beds for multiphase flow studies in the petroleum industry. We present a new me...

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