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奎诺二甲基酯

奎诺二甲基酯用途

酚藏红是一种酚嗪染料。与亲本双链形式相比,酚藏红对三链RNA具有高的结合亲和力,通过插入两种形式的RNA结合。酚藏红可用于植物细胞染色、血红蛋白、多巴胺、血清素等的测定[1][2][3]。

奎诺二甲基酯名称

[ CAS 号 ]:
81-93-6

[ 中文名 ]:
酚藏花红

[ 英文名 ]:
Phenosafranine

[中文别名 ]:

[英文别名 ]:

Phenazinium, 3,7-diamino-5-phenyl-, chloride (1:1)
Phenosafranin
3,7-diamino-5-phenyl phenazinium chloride
MFCD00036335
Phenosafranine
3,7-Diamino-5-phenylphenazin-5-ium chloride
EINECS 201-387-0
Phenosofranine
Safrinin B Extra
Phenosafrinine

奎诺二甲基酯生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Widholm JM. The use of fluorescein diacetate and phenosafranine for determining viability of cultured plant cells. Stain Technol. 1972 Jul;47(4):189-94.

[2]. Liu, W., et al. Characterization of Phenosafranine–Hemoglobin Interactions in Aqueous Solution. J Solution Chem 40, 231–246 (2011).

[3]. Pradhan AB, et al. An overview on the interaction of phenazinium dye phenosafranine to RNA triple and double helices. Int J Biol Macromol. 2016 May;86:345-51.

奎诺二甲基酯物理化学性质

[ 密度 ]:
1.1738 (rough estimate)

[ 沸点 ]:
478.49°C (rough estimate)

[ 熔点 ]:
300ºC

[ 分子式 ]:
C₁₈H₁₅ClN₄

[ 分子量 ]:
322.792

[ 精确质量 ]:
322.098511

[ PSA ]:
68.81000

[ LogP ]:
0.99550

[ 折射率 ]:
1.6110 (estimate)

[ 储存条件 ]:
室温

奎诺二甲基酯MSDS

详细MSDS(安全技术说明书)

奎诺二甲基酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SG1630000

CHEMICAL NAME :: Phenazinium, 3,7-diamino-5-phenyl-, chloride

CAS REGISTRY NUMBER :: 81-93-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C18-H15-N4.Cl

MOLECULAR WEIGHT :: 322.82

WISWESSER LINE NOTATION :: T C666 BK INJ BR& EZ MZ &G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :: Insect - Drosophila melanogaster

DOSE/DURATION :: 1000 ppm

REFERENCE :: AMNTA4 American Naturalist. (Univ. of Chicago Press, Journals Div., POB 37005, Chicago, IL 60637) V.1- 1867- Volume(issue)/page/year: 87,295,1953

奎诺二甲基酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
SG1630000

奎诺二甲基酯文献

Spectrophotometric and spectrofluorometric studies on interaction of cationic dyes with bacterial capsular polysaccharide.

Indian J. Biochem. Biophys. 35(4) , 241-6, (1998)

Interaction of Klebsiella K14 capsular polysaccharide with cationic dyes pinacyanol chloride, acridine orange and phenosafranin has been studied by spectrophotometric and spectrofluorometric technique...

Sulfite Oxidase Catalyzes Single-Electron Transfer at Molybdenum Domain to Reduce Nitrite to Nitric Oxide.

Antioxid. Redox Signal. 23 , 283-94, (2015)

Recent studies suggest that the molybdenum enzymes xanthine oxidase, aldehyde oxidase, and mARC exhibit nitrite reductase activity at low oxygen pressures. However, inhibition studies of xanthine oxid...

A promising dehydrogenase-based bioanode for a glucose biosensor and glucose/O2 biofuel cell.

Analyst 137(9) , 2233-8, (2012)

A new type of dehydrogenase-based amperometric glucose biosensor was constructed using glucose dehydrogenase (GDH) which was immobilized on the edge-plane pyrolytic graphite (EPPG) electrode modified ...

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