1,3-二甲基-2-咪唑啉酮

1,3-二甲基-2-咪唑啉酮用途

【用途一】
可作高功能性反应溶剂，作为聚合物的溶剂，也可用于生产高质量聚酰胺
【用途二】
用作医药中间体，重要的有机溶剂
【用途三】
医药中间体，也是重要的有机溶剂。
【用途四】
DMI广泛应用于化工、医药、农药、染料等精细化学品的合成，同时应用于有机合成、高分子合成、高能电池的电解液、喷墨油墨、水基油墨、催化剂、药物增效剂、特种洗涤剂的添加剂。DMI在美国、西欧和日本在工业上用于化学药物，农用化学和精细化学品合成中的许多反应。

1,3-二甲基-2-咪唑啉酮名称

[ CAS 号 ]:
80-73-9

[ 中文名 ]:
1,3-二甲基-2-咪唑啉酮

[ 英文名 ]:
1,3-Dimethyl-2-imidazolidinone

[中文别名 ]:

[英文别名 ]:

DMI
1,3-DMI
karbomostsem
1,3-Dimethylethyleneurea
1,3-dimethylimidazolin-2-one
1,3-Dimethylimidazolidone
1,3-Dimethyl-2-imida
2-Imidazolidinone, 1,3-dimethyl-
1,3-dimethylimidazolidinone
1,3-Dimethylimidazolidin-2-one

1,3-二甲基-2-咪唑啉酮物理化学性质

[ 密度 ]:
1.044

[ 沸点 ]:
225.5 ºC

[ 熔点 ]:
8.2 °C

[ 分子式 ]:
C₅H₁₀N₂O

[ 分子量 ]:
114.146

[ 闪点 ]:
93 ºC

[ 精确质量 ]:
114.079315

[ PSA ]:
23.55000

[ LogP ]:
-0.03

[ 外观性状 ]:
透明液体

[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C

[ 折射率 ]:
1.480

[ 储存条件 ]:
存放于惰性气体之中;避免湿气 (吸湿)

[ 水溶解性 ]:
freely soluble

1,3-二甲基-2-咪唑啉酮MSDS

详细MSDS(安全技术说明书)

1,3-二甲基-2-咪唑啉酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NJ0660000

CHEMICAL NAME :: 2-Imidazolidinone, 1,3-dimethyl-

CAS REGISTRY NUMBER :: 80-73-9

BEILSTEIN REFERENCE NO. :: 0108808

LAST UPDATED :: 199709

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C5-H10-N2-O

MOLECULAR WEIGHT :: 114.17

WISWESSER LINE NOTATION :: T5NVNTJ A1 C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,191,1992 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1190 uL/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - tremor Skin and Appendages - hair

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,191,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2840 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,214,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 930 uL/kg

TOXIC EFFECTS :: Behavioral - tremor Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - other changes

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,191,1992

1,3-二甲基-2-咪唑啉酮安全信息

[ 符号 ]:

GHS05, GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H318-H361-H373

[ 警示性声明 ]:
P280-P305 + P351 + P338

[ 靶器官 ]:
Testes

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R21/22;R36/38

[ 安全声明 (欧洲) ]:
S26-S36-S36/37/39

[ 危险品运输编码 ]:
UN 2810 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
NJ0660000

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2933399090

1,3-二甲基-2-咪唑啉酮合成路线

详细合成路线

1,3-二甲基-2-咪唑啉酮上下游产品

1,3-二甲基-2-咪唑啉酮上游产品

1,3-二甲基-2-咪唑啉酮下游产品

1,3-二甲基-2-咪唑啉酮制备

首先尿素与乙二胺在乙二醇溶液中进行合环反应生成2-咪唑啉酮，然后2-咪唑啉酮和甲醛及甲酸反应生成1，3-DMI。

1,3-二甲基-2-咪唑啉酮海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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