4-羟基苯甲腈

4-羟基苯甲腈用途

【用途一】
用于生产液晶、医药、染料、农药中间体等
【用途二】
是重要的精细化工原料和中间体，广泛用于合成多种医药、香料、农药、液晶材料和缓蚀剂等
【用途三】
对氰基苯酚又称对羟基苯甲腈(p-hydroxybenzonitrile)，是有机磷杀虫剂杀螟腈和苯腈磷的中间体，又是除草剂溴苯腈的中间体，同时也是液晶材料、香料等的中间体。
【用途四】
对羟基苯腈即对氰基酚，是除草剂溴苯腈和杀虫剂杀螟腈、苯腈磷的中间体。
【用途五】
用机合成中间体，用于生产农药杀螟腈、苯腈磷。
【用途六】
对羟基苯甲腈是极为重要的精细有机化工原料和中间体。广泛用于合成多种医药、香料、农药、液晶材料和缓蚀剂等。

4-羟基苯甲腈名称

[ CAS 号 ]:
767-00-0

[ 中文名 ]:
4-羟基苯甲腈

[ 英文名 ]:
4-Hydroxybenzonitrile

[中文别名 ]:

[英文别名 ]:

para-hydroxybenzonitrile
p-hydroxybenzoic hydrazide
4-Cyanophenol
4-hydroxybenzhydrazide
Benzonitrile, 4-hydroxy-
p-Hydroxybenzhydrazide
p-hydroxybenzoic acid hydrazide
p-Hydroxybenzonitrile
p-hydroxybenzoylhydrazine
4-Hydroxybenzoic acid hydrazide

4-羟基苯甲腈物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
281.2±23.0 °C at 760 mmHg

[ 熔点 ]:
110-113 °C(lit.)

[ 分子式 ]:
C₇H₅NO

[ 分子量 ]:
119.121

[ 闪点 ]:
123.9±22.6 °C

[ 精确质量 ]:
119.037117

[ PSA ]:
44.02000

[ LogP ]:
1.60

[ 外观性状 ]:
白色结晶粉末或芯片

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.591

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
slightly soluble

4-羟基苯甲腈MSDS

详细MSDS(安全技术说明书)

4-羟基苯甲腈毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DI4375000

CHEMICAL NAME :: Benzonitrile, p-hydroxy-

CAS REGISTRY NUMBER :: 767-00-0

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C7-H5-N-O

MOLECULAR WEIGHT :: 119.13

WISWESSER LINE NOTATION :: QR DCN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 41,391,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

4-羟基苯甲腈安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S45-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
DI4375000

[ 包装等级 ]:
I; II; III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
29269095

4-羟基苯甲腈合成路线

详细合成路线

4-羟基苯甲腈上下游产品

4-羟基苯甲腈上游产品

4-羟基苯甲腈下游产品

4-羟基苯甲腈制备

１．对羟基苯甲酸法　由对羟基苯甲酸氨化制得，反应式为：

　２．对甲苯酚法　由对甲苯酚进行氨氧化制得，其反应式为：

　３．对羟基苯甲醛法　由对羟基苯甲醛和盐酸羟胺反应制得，反应式为：

4-羟基苯甲腈海关

[ 海关编码 ]: 2926909090

[ 中文概述 ]:
2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

4-羟基苯甲腈文献

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