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二甲基马来酸酐

二甲基马来酸酐名称

[ CAS 号 ]:
766-39-2

[ 中文名 ]:
2,3-二甲基马来酸酐

[ 英文名 ]:
dimethylmaleic anhydride

[中文别名 ]:

[英文别名 ]:

3,4-dimethylmaleic acid anhydride
1-ethoxy-2-methyl-1-methylselanyl-propene
Dimethylketol
3,4-Dimethyl-2,5-furandione
dimethylmaleic anhydride
2,2'-dimethylmaleic anhydride
3-hydroxy-2-oxobutane
2,5-Furandione, 3,4-dimethyl-
2,3-dimethyl maleic anhydride
pyrocinchonic anhydride

二甲基马来酸酐物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
223.0±0.0 °C at 760 mmHg

[ 熔点 ]:
93-96 °C(lit.)

[ 分子式 ]:
C₆H₆O₃

[ 分子量 ]:
126.110

[ 闪点 ]:
95.6±15.9 °C

[ 精确质量 ]:
126.031693

[ PSA ]:
43.37000

[ LogP ]:
0.82

[ 外观性状 ]:
白色至米色晶体或结晶粉末

[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C

[ 折射率 ]:
1.487

[ 储存条件 ]:
0-6°C

[ 水溶解性 ]:
水溶性：微溶；易溶于：苯,醇,氯仿,乙醚；可溶于：甲苯

二甲基马来酸酐MSDS

二甲基马来酸酐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ON4025000

CHEMICAL NAME :: Maleic anhydride, dimethyl-

CAS REGISTRY NUMBER :: 766-39-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H6-O3

MOLECULAR WEIGHT :: 126.12

WISWESSER LINE NOTATION :: T5VOVJ D1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2600 mg/kg/65W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 19,392,1965

二甲基马来酸酐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S45-S36/37/39-S28A-S26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
ON4025000

[ 海关编码 ]:
2917190090

二甲基马来酸酐合成路线

二甲基马来酸酐上下游产品

二甲基马来酸酐上游产品

二甲基马来酸酐下游产品

二甲基马来酸酐制备

1. 烟草：BU，56；FC，9，18；BU，18；FC，40。

二甲基马来酸酐海关

[ 海关编码 ]: 2917190090

[ 中文概述 ]:
2917190090 其他无环多元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 对苯二甲酸请注明4-CBA值, 对苯二甲酸请注明P-TL酸值, 对苯二甲酸请注明色度, 对苯二甲酸请注明水分

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

二甲基马来酸酐文献

Surface charge switching nanoparticles for magnetic resonance imaging.

Int. J. Pharm. 471(1-2) , 127-34, (2014)

In this study, polypeptide-based nanoparticles [constituted using poly(L-lysine) coupled with deoxycholic acid (DOCA) and conjugated with 2,3-dimethylmaleic acid (DMA)] have high tumor selectivity onc...

Multimeric grain-marked micelles for highly efficient photodynamic therapy and magnetic resonance imaging of tumors.

Int. J. Pharm. 471(1-2) , 166-72, (2014)

Multimeric grain-marked micelles consisting of an inner core micelle (for Fe3O4 encapsulation) and outer multi-grain micelles (for chlorin e6 (Ce6, a model drug) encapsulation) were fabricated using a...

A smart polymeric platform for multistage nucleus-targeted anticancer drug delivery.

Biomaterials 65 , 43-55, (2015)

Tumor cell nucleus-targeted delivery of antitumor agents is of great interest in cancer therapy, since the nucleus is one of the most frequent targets of drug action. Here we report a smart polymeric ...

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