甲基磺酸

甲基磺酸用途

【用途一】
用作溶剂、烷化、酯化和聚合反应的催化剂，也用于医药及电镀行业
【用途二】
用作催化剂
【用途三】
甲烷磺酸是医药和农药的原料，还可用作脱水剂、涂料固化促进剂、纤维处理剂、溶剂，浣化、酯化和聚合反应催化剂。
【用途四】
用作溶剂以及烷化、酯化和聚合反应的催化剂，医药中间体，70% 浓度的用于电镀。

甲基磺酸名称

[ CAS 号 ]:
75-75-2

[ 中文名 ]:
甲烷磺酸

[ 英文名 ]:
Methanesulfonic acid

[中文别名 ]:

[英文别名 ]:

EINECS 200-898-6
Mesic acid
MFCD00007518
methane sulfonic acid
Methanesulfonic acid
Methanesulphonic acid
CH3SO3H
Methylsulfonic acid
Methane sulfonicacid

甲基磺酸物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
167 °C10 mm Hg(lit.)

[ 熔点 ]:
19 °C

[ 分子式 ]:
CH₄O₃S

[ 分子量 ]:
96.106

[ 闪点 ]:
>230 °F

[ 精确质量 ]:
95.988113

[ PSA ]:
62.75000

[ LogP ]:
-1.89

[ 外观性状 ]:
无色至淡黄色液体

[ 蒸汽密度 ]:
3.3 (vs air)

[ 蒸汽压 ]:
1 mm Hg ( 20 °C)

[ 折射率 ]:
1.448

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、碱类分开存放

[ 稳定性 ]:
Stable. Moisture sensitive. Incompatible with amines, bases, water, common metals. Releases a substantial amount of heat when diluted with water (add acid to water with care if diluting).

[ 水溶解性 ]:
水溶性：完全混溶；可溶于：醇,乙醚；微溶：苯；极微溶：甲苯

甲基磺酸MSDS

甲基磺酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: PB1140000

CHEMICAL NAME :: Methanesulfonic acid

CAS REGISTRY NUMBER :: 75-75-2

BEILSTEIN REFERENCE NO. :: 1446024

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C-H4-O3-S

MOLECULAR WEIGHT :: 96.11

WISWESSER LINE NOTATION :: WSQ1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >330 ppm/6H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 48,371,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83577 No. of Facilities: 82 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 1209 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83577 No. of Facilities: 325 (estimated) No. of Industries: 7 No. of Occupations: 13 No. of Employees: 8084 (estimated) No. of Female Employees: 1393 (estimated)

甲基磺酸安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H290-H302 + H312-H314-H335

[ 警示性声明 ]:
P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S36-S45-S1/2-S36/37/39

[ 危险品运输编码 ]:
UN 3265 8/PG 2

[ WGK德国 ]:
1

[ RTECS号 ]:
PB1140000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2904100000

甲基磺酸合成路线

甲基磺酸上下游产品

甲基磺酸上游产品

甲基磺酸下游产品

甲基磺酸制备

由硫氰酸甲酯经硝酸氧化而得。将硝酸及效负水小心加热至80-88℃，分次加入硫氰酸甲酯，温度自动上升至105℃左右。待反应缓和后，加热到120℃、反应5小时，得粗品。将粗品用交换水冲稀，加25%氢氧化钡溶液调至pH值为8-9，过滤。滤液深缩至有结晶析出，结晶用甲醇洗去硝酸根，得甲烷磺酸钡。再将基加入交换水煮沸，趁热加硫酸分解，过滤，滤液减压浓缩至不出水为止，即得成品。另一种制法是由甲基异硫脲硫酸盐经氯化、氧化、水解而得。将甲基异硫脲硫酸盐加入水中，于20-25℃通入氯气，至溶液颜色转黄，并在瓶底出现油层、温度下降、排气管有大量余氯排出等现象，则为反应终点。反应液用氯仿提取，提取液经干燥后在60-62℃常压蒸出氯仿，然后减压蒸馏，收集60-65℃（2.67kPa）馏分，得甲基磺酰氯。将基在搅拌下滴加80℃热水中，保温水解约2h，至反应液内油滴状物完成消失为止。反应液减压浓缩至糖浆状，加水稀释，再减压浓缩至蒸不出水分为止，得甲烷磺酸。

甲基磺酸海关

[ 海关编码 ]: 2904100000

[ 中文概述 ]:
2904100000 仅含磺基的衍生物及其盐和乙酯。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

甲基磺酸文献

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