5’-二磷酸鸟苷二钠

5’-二磷酸鸟苷二钠用途

Guanosine 5'-diphosphate disodium salt 是一种核苷二磷酸。Guanosine 5'-diphosphate 是一种潜在的铁动员剂,可阻断铁调素-铁转运蛋白相互作用并调节白细胞介素-6 (IL-6)/stat-3 途径。

5’-二磷酸鸟苷二钠名称

[ CAS 号 ]:
7415-69-2

[ 中文名 ]:
5'-二磷酸鸟苷二钠

[ 英文名 ]:
Guanosine-5'-diphosphate disodium salt

[中文别名 ]:

[英文别名 ]:

5'-GDP-Na
MFCD00084665
GDP.Na2
5'-GDP,2Na
Einecs 231-026-2
GDP,NA2H
5'-GDP-Na2
5'-GDP 3NA
GUANOSINE-5'-DIPHOSPHORIC ACID,DISODIUM
Guanosine-5'-diphosphatedisodiumsalt

5’-二磷酸鸟苷二钠生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 炎症/免疫

[参考文献]

[1]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097.

5’-二磷酸鸟苷二钠物理化学性质

[ 沸点 ]:
961ºC at 760 mmHg

[ 分子式 ]:
C₁₀H₁₃N₅Na₂O₁₁P₂

[ 分子量 ]:
487.16

[ 闪点 ]:
535ºC

[ 精确质量 ]:
486.988220

[ PSA ]:
277.85000

[ 外观性状 ]:
白色粉末

[ 储存条件 ]:
-20°C

5’-二磷酸鸟苷二钠MSDS

详细MSDS(安全技术说明书)

5’-二磷酸鸟苷二钠安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3.0

5’-二磷酸鸟苷二钠文献

The RasGrf family of mammalian guanine nucleotide exchange factors.

Biochim. Biophys. Acta 1815 , 170-188, (2011)

RasGrf1 and RasGrf2 are highly homologous mammalian guanine nucleotide exchange factors which are able to activate specific Ras or Rho GTPases. The RasGrf genes are preferentially expressed in the cen...

Models for the functions of Arf GAPs.

Semin. Cell. Dev. Biol. 22 , 3-9, (2011)

Arf GAPs (ADP-ribosylation factor GTPase-activating proteins) are essential components of Arf (ADP-ribosylation factor) signaling pathways. Arf GAPs stimulate the hydrolysis of GTP to GDP to transitio...

A novel GDP-dependent pyruvate kinase isozyme from Toxoplasma gondii localizes to both the apicoplast and the mitochondrion.

J. Biol. Chem. 283 , 14041-14052, (2008)

We previously reported a cytosolic pyruvate kinase (EC 2.7.1.40) from Toxoplasma gondii (TgPyKI) that differs from most eukaryotic pyruvate kinases in being regulated by glucose 6-phosphate rather tha...

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