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甲环素磺基水杨酸盐

甲环素磺基水杨酸盐用途

Meclocycline Sulfosalicylate Salt 是一种具有广谱抗菌活性的四环素抗生素,可预防皮肤细菌感染,例如寻常痤疮。

甲环素磺基水杨酸盐名称

[ CAS 号 ]:
73816-42-9

[ 中文名 ]:
磺基水杨酸氯甲烯土霉素

[ 英文名 ]:
Meclocycline Sulfosalicylate Salt

[英文别名 ]:

MeClC6H3CH2B(pin)
3-chloro-5-methylphenylpinacolborane
Meclocycline 2-hydroxy-5-sulfobenzoic acid
MeClC6H3B(pinacolato)
meclocycline 5-sulfosalicylate
1-chloro-3-methylphenyl-5-BPin
meclocycline sulfosalicylate

甲环素磺基水杨酸盐生物活性

[ 描述 ]:

Meclocycline Sulfosalicylate Salt 是一种具有广谱抗菌活性的四环素抗生素,可预防皮肤细菌感染,例如寻常痤疮。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[ 靶点 ]

Bacterial[1]

[参考文献]

[1]. Knutson DD, et al. Meclocycline sulfosalicylate. Topical antibiotic agent for the treatment of acne vulgaris. Cutis. 1981 Feb;27(2):203-4, 208-10.

甲环素磺基水杨酸盐物理化学性质

[ 沸点 ]:
716.4ºC at 760 mmHg

[ 分子式 ]:
C₂₉H₂₇ClN₂O₁₄S

[ 分子量 ]:
695.04800

[ 闪点 ]:
387.1ºC

[ 精确质量 ]:
694.08700

[ PSA ]:
301.90000

[ LogP ]:
2.33370

[ 外观性状 ]:
晶体

[ 储存条件 ]:
2-8°C，惰性气体保存

甲环素磺基水杨酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

甲环素磺基水杨酸盐文献

Topical antibiotics in dermatology.

Arch. Dermatol. 124 , 1691-1700, (1988)

Topical antibiotics are safe and effective in certain conditions, primarily acne, rosacea, and nasal carriage of Staphylococcus aureus. They are useful in impetigo only when it is of limited extent. T...

The use of antibiotics in acne therapy: oral or topical administration?

J. Antimicrob. Chemother. 10 , 89-115, (1982)

Topical v systemic agent treatment for papulopustular acne. A cost-effectiveness analysis.

Arch. Dermatol. 120 , 1571-1578, (1984)

We used cost-effectiveness analysis to compare the costs, risks, and benefits of two strategies for clearing papulopustular acne; topical therapy alone as initial therapy or a combination of systemic ...

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