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萘夫西林钠

萘夫西林钠用途

Nafcillin钠一水合物是青霉素相关的半合成抗生素。

萘夫西林钠名称

[ CAS 号 ]:
7177-50-6

[ 中文名 ]:
萘夫西林钠

[ 英文名 ]:
Nafcillin sodium salt monohydrate

[中文别名 ]:

[英文别名 ]:

nafcillin sodium monohydrate
MFCD01941128
Nafcillin sodium salt monohydrate
NAFCILLINSODIUMSTERILE
nafcillin sodium
Unipen (tn)
Nafcillin monohydrate sodium salt
Nafcillin (sodium monohydrate)

萘夫西林钠生物活性

[ 描述 ]:

Nafcillin钠一水合物是青霉素相关的半合成抗生素。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

[参考文献]

[1]. Tan, A.K. and A.L. Fink, Identification of the site of covalent attachment of nafcillin, a reversible suicide inhibitor of beta-lactamase. Biochem J, 1992. 281 ( Pt 1): p. 191-6.

[2]. Palmer, D.L., S.B. Pett, and B.F. Akl, Bacterial wound colonization after broad-spectrum versus narrow-spectrum antibiotics. Ann Thorac Surg, 1995. 59(3): p. 626-31.

[相关活性小分子]

萘夫西林钠物理化学性质

[ 密度 ]:
1.42 g/cm3

[ 沸点 ]:
714.1ºC at 760 mmHg

[ 分子式 ]:
C₂₁H₂₃N₂NaO₆S

[ 分子量 ]:
454.472

[ 闪点 ]:
385.7ºC

[ 精确质量 ]:
454.117462

[ PSA ]:
133.30000

[ LogP ]:
1.41360

[ 外观性状 ]:
白色粉末

[ 储存条件 ]:
2-8°C

萘夫西林钠安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H315-H317-H319-H334-H335

[ 警示性声明 ]:
P261-P280-P284-P304 + P340-P305 + P351 + P338-P342 + P311

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

萘夫西林钠文献

Effect of NaCl and nafcillin on penicillin-binding protein 2a and heterogeneous expression of methicillin resistance in Staphylococcus aureus.

Antimicrob. Agents Chemother. 31 , 1982-1988, (1987)

Expression of methicillin resistance in heterogeneous strains of Staphylococcus aureus is enhanced by 2 to 5% NaCl in the medium and by selection with beta-lactam antibiotics. Resistance is associated...

Co-trimoxazole versus nafcillin in the therapy of experimental meningitis due to Staphylococcus aureus.

J. Antimicrob. Chemother. 19 , 647-658, (1987)

Co-trimoxazole was compared with nafcillin against Staphylococcus aureus in vitro and in the therapy of experimental Staph. aureus meningitis in rabbits. Co-trimoxazole (trimethoprim:sulphamethoxazole...

更多文献

萘夫西林钠

萘夫西林钠用途

萘夫西林钠名称

萘夫西林钠生物活性

萘夫西林钠物理化学性质

萘夫西林钠安全信息

萘夫西林钠文献

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