Dimethyl fumarate D6
Dimethyl fumarate D6用途
Dimethyl fumarate D6 是 Dimethyl fumarate 的氘代标记物。Dimethyl fumarate 是一种 Nrf2 激活剂,能够诱导上调抗氧化基因的表达。
Dimethyl fumarate D6名称
[ CAS 号 ]:
66487-95-4
[ 英文名 ]:
Dimethyl fumarate d6
Dimethyl fumarate D6生物活性
[ 描述 ]:
Dimethyl fumarate D6 是 Dimethyl fumarate 的氘代标记物。Dimethyl fumarate 是一种 Nrf2 激活剂,能够诱导上调抗氧化基因的表达。
[ 相关类别 ]:
[参考文献]
[1]. Albrecht P, et al. Effects of dimethyl fumarate on neuroprotection and immunomodulation. J Neuroinflammation. 2012 Jul 7;9:163.
[2]. Peng H, et al. Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor κB (NF-κB) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated kinase 1 (MSK1) signaling. J Biol Chem. 2012 Aug 10;287(33):28017-26.
[3]. Meili-Butz S, et al. Dimethyl fumarate, a small molecule drug for psoriasis, inhibits Nuclear Factor-kappaB and reduces myocardial infarct size in rats. Eur J Pharmacol. 2008 May 31;586(1-3):251-8.
[4]. Cross SA, et al. Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection. J Immunol. 2011 Nov 15;187(10):5015-25.
[5]. Jing X, et al. Dimethyl fumarate attenuates 6-OHDA-induced neurotoxicity in SH-SY5Y cells and in animal model of Parkinson's disease by enhancing Nrf2 activity. Neuroscience. 2015 Feb 12;286:131-40.
[6]. Li Y, et al. Dimethyl fumarate accelerates wound healing under diabetic condition. J Mol Endocrinol. 2018 Jul 23. pii: JME-18-0102.
Dimethyl fumarate D6物理化学性质
[ 分子式 ]:
C6H2D6O4
[ 分子量 ]:
150.162290668
推荐生产厂家/供应商：
暂无推荐供应商。请联系客服获知如何成为推荐供应商。
[Dimethyl fumarate D6]化源网提供Dimethyl fumarate D6CAS号66487-95-4，Dimethyl fumarate D6MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询Dimethyl fumarate D6上化源网，专业又轻松。>>电脑版：Dimethyl fumarate D6
标题：66487-95-4_Dimethyl fumarate D6CAS号:66487-95-4_Dimethyl fumarate D6【结构式 性质 英文】 - 化源网 地址：https://www.chemsrc.com/amp/cas/66487-95-4_1540852.html