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1,2,3,4-四氢喹啉

1,2,3,4-四氢喹啉用途

【用途一】
用于有机合成

1,2,3,4-四氢喹啉名称

[ CAS 号 ]:
635-46-1

[ 中文名 ]:
1,2,3,4-四氢喹啉

[ 英文名 ]:
1,2,3,4-Tetrahydroquinoline

[中文别名 ]:

[英文别名 ]:

Kusol
Quinoline, 1,2,3,4-tetrahydro-
(1H)-tetrahydroquinoline
MFCD00006693
2,3,4-trihydroquinoline
Quinoline,1,2,3,4-tetrahydro
1,2,3,4-tetrahydro-quinoline
benzopiperidine
1,3,9,9a-tetrahydroquinoline
tetrahydroquinoline

1,2,3,4-四氢喹啉物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
250.8±10.0 °C at 760 mmHg

[ 熔点 ]:
9-14 °C(lit.)

[ 分子式 ]:
C₉H₁₁N

[ 分子量 ]:
133.190

[ 闪点 ]:
100.6±0.0 °C

[ 精确质量 ]:
133.089142

[ PSA ]:
12.03000

[ LogP ]:
2.29

[ 外观性状 ]:
无色透明或淡黄色液体

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.544

[ 储存条件 ]:
Room temperature.

[ 水溶解性 ]:
<1 g/L (20 ºC)

1,2,3,4-四氢喹啉MSDS

1,2,3,4-四氢喹啉安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H315-H319-H335-H350

[ 警示性声明 ]:
P201-P261-P305 + P351 + P338-P308 + P313

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36/37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
29334990

1,2,3,4-四氢喹啉合成路线

1,2,3,4-四氢喹啉上下游产品

1,2,3,4-四氢喹啉上游产品

1,2,3,4-四氢喹啉下游产品

1,2,3,4-四氢喹啉海关

[ 海关编码 ]: 29334990

1,2,3,4-四氢喹啉文献

Discovery of thienoquinolone derivatives as selective and ATP non-competitive CDK5/p25 inhibitors by structure-based virtual screening.

Bioorg. Med. Chem. 22(22) , 6409-21, (2014)

Calpain mediated cleavage of CDK5 natural precursor p35 causes a stable complex formation of CDK5/p25, which leads to hyperphosphorylation of tau. Thus inhibition of this complex is a viable target fo...

Pharmacokinetic plasma behaviors of intravenous and oral bioavailability of thymoquinone in a rabbit model.

Eur. J. Drug Metab. Pharmacokinet. 40 , 319-23, (2015)

Thymoquinone (THQ), the active constituent of Nigella sativa seeds, has demonstrated some potential pharmacological activities. The present study was designed to investigate the pharmacokinetic behavi...

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