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4-溴苯肼单盐酸盐

4-溴苯肼单盐酸盐用途

【用途一】
应用于染料和医药中间体。

4-溴苯肼单盐酸盐名称

[ CAS 号 ]:
622-88-8

[ 中文名 ]:
4-溴苯肼盐酸盐

[ 英文名 ]:
(4-Bromophenyl)hydrazine hydrochloride

[中文别名 ]:

[英文别名 ]:

4-Bromo Phenyl Hydrazine Hydrochloride
(4-Bromophenyl)hydrazine hydrochloride (1:1)
Hydrazine, (4-bromophenyl)-, hydrochloride (1:1)
4-Bromophenylhydrazine hydrochloride
(4-bromophenyl)hydrazine hydrochloride
(4-Bromphenyl)hydrazinhydrochlorid
4-Bromophenylhydrazinehydrochloride
MFCD00012941
EINECS 255-590-4

4-溴苯肼单盐酸盐物理化学性质

[ 沸点 ]:
285.6ºC at 760 mmHg

[ 熔点 ]:
220-230 °C (dec.)(lit.)

[ 分子式 ]:
C₆H₈BrClN₂

[ 分子量 ]:
223.498

[ 闪点 ]:
126.5ºC

[ 精确质量 ]:
221.955933

[ PSA ]:
38.05000

[ LogP ]:
3.31000

[ 外观性状 ]:
固体

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类、食品添加剂分开存放

4-溴苯肼单盐酸盐MSDS

4-溴苯肼单盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MV0800000

CHEMICAL NAME :: Hydrazine, 1-(p-bromophenyl)-, hydrochloride

CAS REGISTRY NUMBER :: 622-88-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H7-Br-N2.Cl-H

MOLECULAR WEIGHT :: 223.52

WISWESSER LINE NOTATION :: ZMR DE &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947

4-溴苯肼单盐酸盐安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S28A

[ 危险品运输编码 ]:
UN 3261 8/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
MV0800000

[ 危险类别 ]:
8.0

[ 海关编码 ]:
29280090

4-溴苯肼单盐酸盐合成路线

4-溴苯肼单盐酸盐上下游产品

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4-溴苯肼单盐酸盐下游产品

4-溴苯肼单盐酸盐海关

[ 海关编码 ]: 2928000090

[ 中文概述 ]:
2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

4-溴苯肼单盐酸盐文献

Epoxide-containing side chains enhance antiproliferative activity of paullones.

Eur. J. Med. Chem. 40(7) , 655-61, (2005)

The introduction of side chains bearing epoxide motifs into the molecular scaffold of kenpaullone and 9-trifluoromethylpaullone led to improved antiproliferative activity of the novel derivatives for ...

Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor.

Bioorg. Med. Chem. Lett. 18(6) , 1926-30, (2008)

A series of novel acylsulfonamide, acylsulfamide, and sulfonylurea bioisosteres of carboxylic acids were prepared as CXCR2 antagonists. Structure-activity relationships are reported for these series. ...

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