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土霉素二水合物

土霉素二水合物用途

Oxytetracycline dihydrate 是一种广谱抗生素,通过抑制细菌蛋白质合成发挥作用。

土霉素二水合物作用

药理作用该品具有广谱抗菌作用对敏感菌包括肺炎球菌、链球菌、部分葡萄菌、炭疽杆菌、破伤风杆菌、对猪肺炎支原体、衣原体、螺旋体，也有一定的抑制作用。

土霉素二水合物名称

[ CAS 号 ]:
6153-64-6

[ 中文名 ]:
地霉素

[ 英文名 ]:
Oxytetracycline Dihydrate

[中文别名 ]:

[英文别名 ]:

DOXYCYCLINE USP 23
MFCD00151234
trramycin
Oxy-tetracyclin
OXYTETRACYCLINEFEED
OXYCYCLINE
OXYTETRACYCLINE HCL BP
DOXYCYCLINE HYCHLATE
EINECS 209-271-1

土霉素二水合物生物活性

[ 描述 ]:

Oxytetracycline dihydrate 是一种广谱抗生素,通过抑制细菌蛋白质合成发挥作用。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[体外研究]

土霉素二水合物是一种经过充分研究的聚酮化合物天然产物,是II型聚酮化合物生物合成的重要实例[1]。

[参考文献]

[1]. Pickens LB, et al. Oxytetracycline biosynthesis. J Biol Chem. 2010 Sep 3;285(36):27509-15.

土霉素二水合物物理化学性质

[ 沸点 ]:
845.6ºC at 760 mmHg

[ 熔点 ]:
181-182 °C

[ 分子式 ]:
C₂₂H₂₈N₂O₁₁

[ 分子量 ]:
496.46500

[ 闪点 ]:
465.2ºC

[ 精确质量 ]:
496.16900

[ PSA ]:
220.31000

[ 外观性状 ]:
结晶

[ 储存条件 ]:
2~8°C

[ 水溶解性 ]:
slightly soluble

土霉素二水合物MSDS

详细MSDS(安全技术说明书)

土霉素二水合物安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R36;R63

[ 安全声明 (欧洲) ]:
S22-S24/25-S36/37/39-S26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
29413000

土霉素二水合物海关

[ 海关编码 ]: 29413000

土霉素二水合物文献

Experimental study of the impact of antimicrobial treatments on Campylobacter, Enterococcus and PCR-capillary electrophoresis single-strand conformation polymorphism profiles of the gut microbiota of chickens.

J. Med. Microbiol. 63(Pt 11) , 1552-60, (2014)

An experiment was conducted to compare the impact of antimicrobial treatments on the susceptibility of Campylobacter, Enterococcus faecium and Enterococcus faecalis, and on the diversity of broiler mi...

Development and validation of a liquid chromatographic/ tandem mass spectrometric method for determination of chlortetracycline, oxytetracycline, tetracycline, and doxycycline in animal feeds.

J. AOAC Int. 95(4) , 1010-5, (2012)

A selective and accurate LC/MS/MS method for the simultaneous determination of chlortetracycline (CTC), oxytetracycline (OTC), tetracycline (TC), and doxycycline (DC) in animal feeds was developed. Sa...

Heterologous expression and manipulation of three tetracycline biosynthetic pathways.

Angew. Chem. Int. Ed. Engl. 51(44) , 11136-40, (2012)

A very accommodating host: Three tetracycline biosynthetic pathways were overexpressed and manipulated in the heterologous host Streptomyces lividans K4-114. Through the inactivation of various genes ...

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