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十六烷基氯化吡啶

十六烷基氯化吡啶用途

氯化十六烷吡啶单水合物是一种阳离子季铵化合物, 用于某些类型的漱口水, 牙膏, 咽喉和鼻腔喷雾剂中, 是一种能杀死细菌和其他微生物的防腐剂, 可有效预防牙斑和减少牙龈炎。

十六烷基氯化吡啶名称

[ CAS 号 ]:
6004-24-6

[ 中文名 ]:
十六烷基氯化吡啶

[ 英文名 ]:
Cetylpyridinium chloride monohydrate

[中文别名 ]:

[英文别名 ]:

Cetylpyridinum chloride
Cetylpyridinium chloride monohydrate
CETYLPYRIDINII CHLORIDUM
MFCD00149977
CPC MONOHYDRATE
EINECS 204-593-9
cetylpyridinium chloride
Chlorohexadecyl pyridine
Ceetylpyridiniumchloride
1-Hexadecylpyridin-1-ium chloride hydrate

十六烷基氯化吡啶生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

[相关活性小分子]

十六烷基氯化吡啶物理化学性质

[ 熔点 ]:
81-84 °C

[ 分子式 ]:
C₂₁H₄₀ClNO

[ 分子量 ]:
358.001

[ 精确质量 ]:
357.279846

[ PSA ]:
13.11000

[ LogP ]:
3.39510

[ 外观性状 ]:
白色至淡米色粉末

[ 储存条件 ]:
库房低温通风干燥,与食品原料分开存放

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid anhydrides, acid chlorides.

十六烷基氯化吡啶MSDS

详细MSDS(安全技术说明书)

十六烷基氯化吡啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU5075000

CHEMICAL NAME :: Pyridinium, 1-hexadecyl-, chloride, monohydrate

CAS REGISTRY NUMBER :: 6004-24-6

LAST UPDATED :: 199603

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C21-H38-N.Cl.H2-O

MOLECULAR WEIGHT :: 358.07

WISWESSER LINE NOTATION :: T6KJ A16 &G &QH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

十六烷基氯化吡啶安全信息

[ 符号 ]:

GHS06, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H315-H319-H330-H335-H410

[ 警示性声明 ]:
P260-P304 + P340 + P310-P305 + P351 + P338-P403 + P233

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T+:Verytoxic;

[ 风险声明 (欧洲) ]:
R25;R26;R38

[ 安全声明 (欧洲) ]:
S28-S36/37-S45-S7/9-S61-S26

[ 危险品运输编码 ]:
UN 2811 6.1/PG 1

[ WGK德国 ]:
3

[ RTECS号 ]:
UU5075000

[ 包装等级 ]:
I

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2933399090

十六烷基氯化吡啶制备

将氯代十六烷和干吡啶油浴加热反应，再加入丙酮，混合物水浴加热溶解后再冷却得到产品。

十六烷基氯化吡啶海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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