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腺苷-5'-二磷酸

腺苷-5'-二磷酸用途

1.生化研究。

腺苷-5'-二磷酸名称

[ CAS 号 ]:
58-64-0

[ 中文名 ]:
腺苷-5’-二磷酸

[ 英文名 ]:
Adenosine diphosphate

[中文别名 ]:

[英文别名 ]:

Adenosine diphosphate (6CI)
Adenosine trihydrogen diphosphate
adenosine 5’-diphosphate
Adenosine, 5'-(trihydrogen diphosphate)
Adenosine 5'-diphosphate
Adenosine 5′-diphosphate
adenosine-5-diphosphate
MFCD00066473
EINECS 200-392-5
Adenosine 5'-(trihydrogen diphosphate)

腺苷-5'-二磷酸生物活性

[ 描述 ]:

Adenosine 5'-diphosphate 是核苷二磷酸,是 ATP 酶对 ATP 去磷酸化的产物。

[ 相关类别 ]:

天然产物 >> 酸和醛

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[体外研究]

腺苷5'-二磷酸由焦磷酸基团,戊糖糖核糖和核碱基腺嘌呤组成。腺苷5'-二磷酸是ATP酶对ATP去磷酸化的产物。通过ATP合酶将ADP转化回ATP。 ATP是细胞中重要的能量转移分子。腺苷5'-二磷酸用于许多细胞过程,包括呼吸,生物合成反应,运动和细胞分裂。

[相关活性小分子]

腺苷-5'-二磷酸物理化学性质

[ 密度 ]:
2.5±0.1 g/cm3

[ 沸点 ]:
877.7±75.0 °C at 760 mmHg

[ 分子式 ]:
C₁₀H₁₅N₅O₁₀P₂

[ 分子量 ]:
427.201

[ 闪点 ]:
484.6±37.1 °C

[ 精确质量 ]:
427.029419

[ PSA ]:
252.22000

[ LogP ]:
-2.91

[ 外观性状 ]:
白色到灰白色粉末

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.905

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

腺苷-5'-二磷酸MSDS

腺苷-5'-二磷酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7467000

CHEMICAL NAME :: Adenosine, 5'-(trihydrogen pyrophosphate)

CAS REGISTRY NUMBER :: 58-64-0

BEILSTEIN REFERENCE NO. :: 0067722

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H15-N5-O10-P2

MOLECULAR WEIGHT :: 427.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3333 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Human Cells - not otherwise specified

DOSE/DURATION :: 100 umol/L

REFERENCE :: JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 65,52,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3804 No. of Facilities: 622 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 8666 (estimated) No. of Female Employees: 6878 (estimated)

腺苷-5'-二磷酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
AU7467000

[ 海关编码 ]:
29349990

腺苷-5'-二磷酸合成路线

腺苷-5'-二磷酸上下游产品

腺苷-5'-二磷酸上游产品

腺苷-5'-二磷酸下游产品

腺苷-5'-二磷酸制备

由5′-腺苷酸为原料制取。

腺苷-5'-二磷酸文献

Investigation of NADH binding, hydride transfer, and NAD(+) dissociation during NADH oxidation by mitochondrial complex I using modified nicotinamide nucleotides.

Biochemistry 52(23) , 4048-55, (2013)

NADH:ubiquinone oxidoreductase (complex I) is a complicated respiratory enzyme that conserves the energy from NADH oxidation, coupled to ubiquinone reduction, as a proton motive force across the mitoc...

Comprehensive quantitative analysis of purines and pyrimidines in the human malaria parasite using ion-pairing ultra-performance liquid chromatography-mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 127-33, (2014)

Targeted metabolite profiling has aided in the understanding of a variety of biological processes in the malaria parasite as well as in drug discovery. A fast and sensitive analytical method, based on...

Diagnostic use of cerebral and extracerebral oxysterols.

Clin. Chem. Lab Med. 42(2) , 186-91, (2004)

24S-Hydroxycholesterol (24OHC) and 27-hydroxycholesterol (27OHC) are two structurally similar oxysterols of different origins--the former almost exclusively formed in the brain and the latter formed t...

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