1,2-二[反式-9-十八碳烯酰基]-Sn-甘油-3-磷酰胆碱

用途

18:1 (Δ9-Trans) PC (1,2-dielaidoyl-sn-glycero-3-phosphocholine) can help paclitaxel in forming thermodynamically stable systems. It has efficient drug penetration ability into the lipid monolayers when compared to other lipids.

名称

[ CAS 号 ]:
56782-46-8

[ 中文名 ]:
1,2-二乙酰基-sn-甘油-3-磷酸胆碱

[ 英文名 ]:
1,2-dielaidoyl-sn-glycero-3-phosphocholine

[英文别名 ]:

物理化学性质

[ 分子式 ]:
C₄₄H₈₄NO₈P

[ 分子量 ]:
786.11300

[ 精确质量 ]:
785.59300

[ PSA ]:
121.00000

[ LogP ]:
12.79440

[ 外观性状 ]:
固体

[ 储存条件 ]:
20°C

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Membrane dipole modifiers modulate single-length nystatin channels via reducing elastic stress in the vicinity of the lipid mouth of a pore.

Biochim. Biophys. Acta 1848(1 Pt A) , 192-9, (2015)

The polyene antifungal antibiotic nystatin confers its biological activity by forming pores in the membranes of target cells. Exposure of only one side of the membrane to nystatin is more relevant tha...

Transient pearling and vesiculation of membrane tubes under osmotic gradients.

Faraday Discuss. 161 , 167-76; discussion 273-303, (2013)

We report the experimental observation of osmotically induced transient pearling instabilities in vesicular membranes. Giant phospholipid vesicles subjected to negative osmotic gradient, which drives ...

Effects of pyrenebutyrate on the translocation of arginine-rich cell-penetrating peptides through artificial membranes: recruiting peptides to the membranes, dissipating liquid-ordered phases, and inducing curvature.

Biochim. Biophys. Acta 1828(9) , 2134-42, (2013)

Arginine-rich cell-penetrating peptides, including octaarginine (R8) and HIV-1 TAT peptides, have the ability to translocate through cell membranes and transport exogenous bioactive molecules into cel...

更多文献

1,2-二[反式-9-十八碳烯酰基]-Sn-甘油-3-磷酰胆碱

用途

名称

物理化学性质

MSDS

详细MSDS(安全技术说明书)

安全信息

文献

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