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苯赖加压素

苯赖加压素用途

Felypressin是Vasopressin 1激动剂,能够影响精氨酸所有的vasopressin receptor 1As。

苯赖加压素名称

[ CAS 号 ]:
56-59-7

[ 中文名 ]:
苯赖加压素

[ 英文名 ]:
Felypressin

[中文别名 ]:

2-苯丙氨酸-8-赖氨酸加压素

[英文别名 ]:

(2-L-Phenylalanine)-8-lysinevasopressin
Felypressine
M.W. 1040.22 C46H65N13O11S2
Felypressin Acetate
2-(Phenylalanine)-8-lysine vasopressin
felypressin
[PHE2,LYS8]-VASOPRESSIN
2-(L-Phenylalanine)-8-L-lysinevasopressin
Octapressin
MFCD00868221

苯赖加压素生物活性

[ 描述 ]:

Felypressin是Vasopressin 1激动剂,能够影响精氨酸所有的vasopressin receptor 1As。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 心血管疾病

[参考文献]

[1]. Bronzo AL et al. Felypressin increases blood pressure during dental procedures in hypertensive patients. Arq Bras Cardiol. 2012 Aug;99(2):724-31.

[2]. Cecanho R et al. Cardiovascular effects of felypressin. Anesth Prog. 2006 Winter;53(4):119-25.

[相关活性小分子]

苯赖加压素物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
1571.3±65.0 °C at 760 mmHg

[ 熔点 ]:
254-257 °C

[ 分子式 ]:
C₄₆H₆₅N₁₃O₁₁S₂

[ 分子量 ]:
1040.219

[ 闪点 ]:
904.1±34.3 °C

[ 精确质量 ]:
1039.436768

[ PSA ]:
455.92000

[ LogP ]:
-5.00

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.574

[ 储存条件 ]:
室温，干燥

苯赖加压素MSDS

详细MSDS(安全技术说明书)

苯赖加压素安全信息

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

苯赖加压素文献

Ex vivo correlation of the permeability of metoprolol across human and porcine buccal mucosa.

J. Pharm. Sci. 103(7) , 2053-61, (2014)

The pH partition theory proposes a correlation between fraction of unionized drug substance and permeability. The aim of this study was to compare the permeability of metoprolol and mannitol in ex viv...

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental treatment in children and adolescents.

Cochrane Database Syst. Rev. 12 , CD009742, (2014)

Whilst carrying out dental procedures under general anaesthesia (GA), practitioners routinely give local anaesthetics (LA) intraoperatively to children. Local anaesthetics are used to help manage post...

Octopus, which owns the most advanced brain in invertebrates, has two members of vasopressin/oxytocin superfamily as in vertebrates.

Regul. Pept. 115(2) , 139-49, (2003)

A novel member of the vasopressin/oxytocin superfamily, octopressin (OP), has been isolated from Octopus vulgaris. Since another peptide of this superfamily, cephalotocin (CT), was isolated from the s...

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