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硫酸双氢链霉素

硫酸双氢链霉素用途

Dihydrostreptomycin硫酸盐是一种氨基糖苷类抗生素, 用于治疗牛, 猪和羊的细菌性疾病。

硫酸双氢链霉素名称

[ CAS 号 ]:
5490-27-7

[ 中文名 ]:
硫酸双氢链霉素

[ 英文名 ]:
Dihydrostreptomycin sulfate

[中文别名 ]:

[英文别名 ]:

Dihydrostreptomycin sulfate

硫酸双氢链霉素生物活性

[ 描述 ]:

Dihydrostreptomycin硫酸盐是一种氨基糖苷类抗生素, 用于治疗牛, 猪和羊的细菌性疾病。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

[相关活性小分子]

硫酸双氢链霉素物理化学性质

[ 沸点 ]:
954.5ºC at 760 mmHg

[ 分子式 ]:
C₂₁H₄₁N₇O_12.3/₂H₂SO₄

[ 分子量 ]:
730.71

[ 闪点 ]:
531.1ºC

[ PSA ]:
927.35000

[ 外观性状 ]:
白色或类白色结晶性粉末

[ 储存条件 ]:
2-8°C

硫酸双氢链霉素MSDS

详细MSDS(安全技术说明书)

硫酸双氢链霉素毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WK2236000

CAS REGISTRY NUMBER :: 5490-27-7

LAST UPDATED :: 199801

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C21-H41-N7-O12.3/2H2-O4-S

MOLECULAR WEIGHT :: 730.74

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 841 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 4,564,1956/1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 186 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 4,564,1956/1967 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 19598 mg/kg/78D-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Ear) - change in acuity

REFERENCE :: ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 4,564,1956/1957 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1292 No. of Facilities: 413 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 4059 (estimated) No. of Female Employees: 2035 (estimated)

硫酸双氢链霉素安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
22

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
WK2236000

[ 海关编码 ]:
2941200000

硫酸双氢链霉素海关

[ 海关编码 ]: 2941200000

硫酸双氢链霉素文献

Mixed-mode liquid chromatography coupled to tandem mass spectrometry for the analysis of aminoglycosides in meat.

Anal. Bioanal. Chem 406(20) , 4941-53, (2014)

A novel LC-MS/MS method has been developed for the determination of 13 aminoglycoside antibiotics in meat products. Among the chromatographic columns tested, the mixed-mode Obelisc R provided the best...

Use of experimental design to optimize a triple-potential waveform to develop a method for the determination of streptomycin and dihydrostreptomycin in pharmaceutical veterinary dosage forms by HPLC-PAD.

J. Pharm. Biomed. Anal. 104 , 81-9, (2014)

An HPLC-PAD method using a gold working electrode and a triple-potential waveform was developed for the simultaneous determination of streptomycin and dihydrostreptomycin in veterinary drugs. Glucose ...

Aminoglycoside analysis in food of animal origin with a zwitterionic stationary phase and liquid chromatography-tandem mass spectrometry.

Anal. Chim. Acta 882 , 127-39, (2015)

In this study, fourteen highly polar aminoglycoside (AGs) antibiotics were selected. Various stationary phases were tested, including Obelisc R, ZIC-HILIC, BEH amide and aminopropyl. The nature of the...

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