<生产厂家价格>

苏木精

苏木精用途

Hematoxylin 是一种天然产物。

苏木精名称

[ CAS 号 ]:
517-28-2

[ 中文名 ]:
苏木精

[ 英文名 ]:
Hematoxylin

[中文别名 ]:

[英文别名 ]:

Hematoxylin Hydrate
MFCD00005394
HAEMATOXYLIN(RG)
bematoxylin
Hematoxylin
Natural Black 1
Natural Black 1 Hydrate
Haematoxylin
Homaeoxylin
hydroxybrazilin

苏木精生物活性

[ 描述 ]:

Hematoxylin 是一种天然产物。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

天然产物 >> 酚类

[参考文献]

[1]. EF Kingston, et al. Vascular invasion is underrecognized in colorectal cancer using conventional hematoxylin and eosin staining. 《Diseases of the Colon & Rectum》, 2007, 50(11):1867-1872

[2]. JE Grilley-Olson, et al. Validation of interobserver agreement in lung cancer assessment: hematoxylin-eosin diagnostic reproducibility for non-small cell lung cancer: the 2004 World Health Organization classification and therapeutically relevant subsets.

[3]. HR Zare, et al. Simultaneous determination of ascorbic acid, adrenaline and uric acid at a hematoxylin multi-wall carbon nanotube modified glassy carbon electrode. Sensors & Actuators B Chemical, 2010, 143(2):666-672

[相关活性小分子]

苏木精物理化学性质

[ 密度 ]:
1.7±0.1 g/cm3

[ 沸点 ]:
579.9±50.0 °C at 760 mmHg

[ 熔点 ]:
200 °C (dec.)(lit.)

[ 分子式 ]:
C₁₆H₁₄O₆

[ 分子量 ]:
302.279

[ 闪点 ]:
304.5±30.1 °C

[ 精确质量 ]:
302.079041

[ PSA ]:
110.38000

[ LogP ]:
0.51

[ 外观性状 ]:
褐色结晶粉末

[ 蒸汽压 ]:
0.0±1.7 mmHg at 25°C

[ 折射率 ]:
1.810

[ 储存条件 ]:
Store at RT.

[ 稳定性 ]:
Stability Stable, but may discolour on exposure to light. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
溶于热水

苏木精MSDS

详细MSDS(安全技术说明书)

苏木精毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MH7875000

CHEMICAL NAME :: Hematoxylin

CAS REGISTRY NUMBER :: 517-28-2

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C16-H14-O6

MOLECULAR WEIGHT :: 302.30

WISWESSER LINE NOTATION :: T C6 B566 LO&TT&J EQ FQ JQ NQ OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg/26W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - lymphoma, including Hodgkin's disease

REFERENCE :: GASTAB Gastroenterology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1943- Volume(issue)/page/year: 23,1,1953 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80980 No. of Facilities: 667 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 3015 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80980 No. of Facilities: 1405 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 24188 (estimated) No. of Female Employees: 20340 (estimated)

苏木精安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P301 + P312 + P330-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
MH7875000

[ 海关编码 ]:
3302101000

苏木精制备

由苏木的芯材水浸提取，再经精制而制得。

苏木精海关

[ 海关编码 ]: 2906299090

[ 中文概述 ]:
2906299090 其他芳香醇. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

苏木精文献

Genetic and pharmacologic inhibition of eIF4E reduces breast cancer cell migration, invasion, and metastasis.

Cancer Res. 75(6) , 1102-12, (2015)

The translation initiation factor eIF4E is an oncogene that is commonly overexpressed in primary breast cancers and metastases. In this article, we report that a pharmacologic inhibitor of eIF4E funct...

Intraplacental gene therapy with Ad-IGF-1 corrects naturally occurring rabbit model of intrauterine growth restriction.

Hum. Gene Ther. 26(3) , 172-82, (2015)

Intrauterine growth restriction (IUGR) due to placental insufficiency is a leading cause of perinatal complications for which there is no effective prenatal therapy. We have previously demonstrated th...

Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking.

Autophagy 10(7) , 1241-55, (2014)

Glioblastoma is one of the most aggressive human cancers with poor prognosis, and therefore a critical need exists for novel therapeutic strategies for management of glioblastoma patients. Itraconazol...

更多文献

苏木精