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双(1,3-二乙基硫代巴比妥酸)三次甲基氧杂菁

双(1,3-二乙基硫代巴比妥酸)三次甲基氧杂菁用途

DiSBAC2(3)是一种阴离子膜电位敏感染料。DiSBAC2(3)是一种质膜电位指示剂[1][2]。

双(1,3-二乙基硫代巴比妥酸)三次甲基氧杂菁名称

[ CAS 号 ]:
47623-98-3

[ 中文名 ]:
双-(1,3-二乙基硫代巴比妥酸)三亚甲基氧醇染料

[ 英文名 ]:
Bis-(1,3-diethylthiobarbituric acid)trimethine oxonol

[中文别名 ]:

双(1,3-二乙基硫代巴比妥酸)三次甲基氧杂菁

[英文别名 ]:

EINECS 256-325-5

双(1,3-二乙基硫代巴比妥酸)三次甲基氧杂菁生物活性

[ 描述 ]:

DiSBAC2(3)是一种阴离子膜电位敏感染料。DiSBAC2(3)是一种质膜电位指示剂[1][2]。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

[参考文献]

[1]. Tatsuya Yoshimura, et al. Combined use of two membrane-potential-sensitive dyes for determination of the Galvani potential difference across a biomimetic oil/water interface. Anal Bioanal Chem. 2014 May;406(14):3407-14.

[2]. P Weisová, et al. Latrepirdine is a potent activator of AMP-activated protein kinase and reduces neuronal excitability. Transl Psychiatry. 2013 Oct 22;3(10):e317.

双(1,3-二乙基硫代巴比妥酸)三次甲基氧杂菁物理化学性质

[ 密度 ]:
1.42g/cm3

[ 沸点 ]:
464.7ºC at 760 mmHg

[ 分子式 ]:
C₁₉H₂₄N₄O₄S₂

[ 分子量 ]:
436.54800

[ 闪点 ]:
234.8ºC

[ 精确质量 ]:
436.12400

[ PSA ]:
145.42000

[ LogP ]:
0.82780

[ 折射率 ]:
1.684

[ 储存条件 ]:
-20°C

双(1,3-二乙基硫代巴比妥酸)三次甲基氧杂菁MSDS

详细MSDS(安全技术说明书)

双(1,3-二乙基硫代巴比妥酸)三次甲基氧杂菁安全信息

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

双(1,3-二乙基硫代巴比妥酸)三次甲基氧杂菁文献

Membrane potential changes visualized in complete growth media through confocal laser scanning microscopy of bis-oxonol-loaded cells.

Exp. Cell Res. 231(2) , 260-8, (1997)

Confocal laser scanning microscopy (CLSM) was employed to visualize and measure membrane potential changes in several types of cultured adherent cells, such as human fibroblasts, mouse mammary tumor C...

Peroxynitrite affects Ca2+ influx through voltage-dependent calcium channels.

J. Neurochem. 76(2) , 341-50, (2001)

The effect of peroxynitrite (OONO-) on voltage-dependent Ca2+ channels (VDCCs) was examined by measuring [45Ca2+] influx into mouse cerebral cortical neurones. OONO- time- and dose-dependently increas...

Simultaneous mechanical stiffness and electrical potential measurements of living vascular endothelial cells using combined atomic force and epifluorescence microscopy.

Nanotechnology 20(17) , 175104, (2009)

The degree of mechanical stiffness of vascular endothelial cells determines the endogenous production of the vasodilating gas nitric oxide (NO). However, the underlying mechanisms are not yet understo...

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