Rifamycin SV, 8-(diethylaminomethyl)-

Rifamycin SV, 8-(diethylaminomethyl)-名称

[ CAS 号 ]:
4075-41-6

[ 英文名 ]:
Rifamycin SV, 8-(diethylaminomethyl)-

[英文别名 ]:

Rifamycin SV, 8-(diethylaminomethyl)-物理化学性质

[ 密度 ]:
1.3g/cm3

[ 沸点 ]:
877.6ºC at 760 mmHg

[ 分子式 ]:
C42H58N2O12

[ 分子量 ]:
782.91600

[ 闪点 ]:
484.5ºC

[ 精确质量 ]:
782.39900

[ PSA ]:
204.55000

[ LogP ]:
5.73390

[ 折射率 ]:
1.618

Rifamycin SV, 8-(diethylaminomethyl)-毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KD1920250
CHEMICAL NAME :
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy -8-(diethylaminomethy l)-, 21-acetate
CAS REGISTRY NUMBER :
4075-41-6
LAST UPDATED :
199712
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C42-H58-N2-O12
MOLECULAR WEIGHT :
783.02

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 12,155,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 12,155,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
205 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,531,1977

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