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黑介子苷

黑介子苷用途

Sinigrin 是十字花科植物中主要的硫代葡萄糖苷,具有抗脂肪生成作用。

黑介子苷名称

[ CAS 号 ]:
3952-98-5

[ 中文名 ]:
黑芥子苷

[ 英文名 ]:
Sinigrin

[中文别名 ]:

[英文别名 ]:

(−)-Sinigrin hydrate
Allyl glucosinolate
Myronate Potassium
Potassium Myronate
MFCD00149447
Sinigroside
EINECS 223-545-8
Sinigrin Hydrate
Sinigrin

黑介子苷生物活性

[ 描述 ]:

Sinigrin 是十字花科植物中主要的硫代葡萄糖苷,具有抗脂肪生成作用。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[参考文献]

[1]. Lee HW, et al. Inhibitory effect of sinigrin on adipocyte differentiation in 3T3-L1 cells: Involvement of AMPK and MAPK pathways. Biomed Pharmacother. 2018 Jun;102:670-680.

黑介子苷物理化学性质

[ 熔点 ]:
128 (dec.)(lit.)ºC

[ 分子式 ]:
C₁₀H₁₆KNO₉S₂

[ 分子量 ]:
415.479

[ 精确质量 ]:
415.000916

[ PSA ]:
202.62000

[ 外观性状 ]:
白色至米色结晶粉末

[ 储存条件 ]:
-20°C，避光，惰性气体

[ 水溶解性 ]:
almost transparency

黑介子苷MSDS

详细MSDS(安全技术说明书)

黑介子苷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ5778000

CHEMICAL NAME :: Glucopyranose, 1-thio-, 1-(3-butenohydroximate) NO-(hydrogensulfate), monopotassium salt, beta-D-

CAS REGISTRY NUMBER :: 3952-98-5

LAST UPDATED :: 199712

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H16-N-O9-S2.K

MOLECULAR WEIGHT :: 397.49

WISWESSER LINE NOTATION :: T6OTJ BSY2U1&UNOSWO CQ DQ EQ F1Q &-KA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 644 mg/kg

SEX/DURATION :: female 8-9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 644 mg/kg

SEX/DURATION :: female 8-9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 4600 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 348,19,1995

黑介子苷安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
LZ5778000

[ 海关编码 ]:
29389090

黑介子苷上下游产品

黑介子苷上游产品

黑介子苷下游产品

黑介子苷文献

Interactive effects of sulfur and nitrogen supply on the concentration of sinigrin and allyl isothiocyanate in Indian mustard (Brassica juncea L.).

J. Agric. Food Chem. 57(9) , 3837-44, (2009)

Food derived from Brassica species is rich in glucosinolates. Hydrolysis of these compounds by myrosinase yields isothiocyanates and other breakdown products, which due to their pungency represent the...

Multidirectional time-dependent effect of sinigrin and allyl isothiocyanate on metabolic parameters in rats.

Plant Foods Hum. Nutr. 65(3) , 217-24, (2010)

Sinigrin (SIN) and allyl isothiocyanate (AITC) are compounds found in high concentrations in Brassica family vegetables, especially in Brussels sprouts. Recently, they have been used as a nutrition su...

Allyl isothiocyanate-rich mustard seed powder inhibits bladder cancer growth and muscle invasion.

Carcinogenesis 31(12) , 2105-10, (2010)

Allyl isothiocyanate (AITC), which occurs in many common cruciferous vegetables, was recently shown to be selectively delivered to bladder cancer tissues through urinary excretion and to inhibit bladd...

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