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咪唑烷基脲

咪唑烷基脲用途

【用途一】
用于化妆品工业中，是除尼泊金酯之外使用最广泛的防腐剂

咪唑烷基脲名称

[ CAS 号 ]:
39236-46-9

[ 中文名 ]:
咪唑烷基脲

[ 英文名 ]:
Imidazolidinyl urea

[中文别名 ]:

[英文别名 ]:

Imidazolidinyl urea
EINECS 254-372-6
Imidurea
MFCD00221482

咪唑烷基脲生物活性

[ 描述 ]:

Imidazolidinyl urea是一种化妆品中使用的抗菌防腐剂, 用作甲醛释放剂。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

[相关活性小分子]

咪唑烷基脲物理化学性质

[ 密度 ]:
1.9±0.1 g/cm3

[ 分子式 ]:
C₁₁H₁₆N₈O₈

[ 分子量 ]:
388.293

[ 精确质量 ]:
388.109100

[ PSA ]:
221.54000

[ LogP ]:
-5.36

[ 外观性状 ]:
白色流体粉末,带有淡特有的气味

[ 折射率 ]:
1.715

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable.

[ 水溶解性 ]:
soluble

咪唑烷基脲MSDS

详细MSDS(安全技术说明书)

咪唑烷基脲毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YT7365000

CHEMICAL NAME :: Urea, N,N''-methylenebis(N'-(1-(hydroxymethyl)-2,5-dioxo-4- imidazolidinyl)-

CAS REGISTRY NUMBER :: 39236-46-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C11-H16-N8-O8

MOLECULAR WEIGHT :: 388.35

WISWESSER LINE NOTATION :: T5NVMV EHJ A1Q EMVM1MVM- ET5NVMV EHJ A1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 11300 mg/kg

TOXIC EFFECTS :: Gastrointestinal - ulceration or bleeding from stomach Gastrointestinal - ulceration or bleeding from duodenum Gastrointestinal - hypermotility, diarrhea

REFERENCE :: JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 4(4),133,1980

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Gastrointestinal - ulceration or bleeding from stomach Gastrointestinal - ulceration or bleeding from duodenum Gastrointestinal - hypermotility, diarrhea

REFERENCE :: JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 4(4),133,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7200 mg/kg

TOXIC EFFECTS :: Gastrointestinal - ulceration or bleeding from stomach Gastrointestinal - ulceration or bleeding from duodenum Gastrointestinal - hypermotility, diarrhea

REFERENCE :: JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 4(4),133,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4906 No. of Facilities: 1885 (estimated) No. of Industries: 7 No. of Occupations: 17 No. of Employees: 28769 (estimated) No. of Female Employees: 18644 (estimated)

咪唑烷基脲安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
YT7365000

[ 海关编码 ]:
2933290090

咪唑烷基脲制备

烷基咪唑衍生物与甲醛反应制得。

咪唑烷基脲海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%