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二唑丁酮

二唑丁酮用途

Climbazole是一种外用抗真菌剂, 常用于治疗人体皮肤真菌感染, 如头皮屑和湿疹。

二唑丁酮名称

[ CAS 号 ]:
38083-17-9

[ 中文名 ]:
氯咪巴唑

[ 英文名 ]:
Climbazole

[中文别名 ]:

[英文别名 ]:

Crinipan AD
CLIMBAZOL
MFCD00055505
baypival
RadixAsteris
EINECS 253-775-4
bay-e6975
BAYSAN
Diadimefon
Climbazole

二唑丁酮生物活性

[ 描述 ]:

Climbazole是一种外用抗真菌剂, 常用于治疗人体皮肤真菌感染, 如头皮屑和湿疹。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 真菌

研究领域 >> 感染

[相关活性小分子]

二唑丁酮物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
447.5±40.0 °C at 760 mmHg

[ 熔点 ]:
96-100°C

[ 分子式 ]:
C₁₅H₁₇ClN₂O₂

[ 分子量 ]:
292.761

[ 闪点 ]:
224.4±27.3 °C

[ 精确质量 ]:
292.097870

[ PSA ]:
44.12000

[ LogP ]:
3.25

[ 外观性状 ]:
灰白色至淡黄色结晶粉末

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.561

[ 储存条件 ]:
-20°C Freezer

二唑丁酮MSDS

详细MSDS(安全技术说明书)

二唑丁酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EL7085000

CHEMICAL NAME :: 2-Butanone, 1-(p-chlorophenoxy)-3,3-dimethyl-1-(1-imidazolyl)-

CAS REGISTRY NUMBER :: 38083-17-9

BEILSTEIN REFERENCE NO. :: 0618020

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H17-Cl-N2-O2

MOLECULAR WEIGHT :: 292.79

WISWESSER LINE NOTATION :: T5N CNJ AYOR DG&VX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,832,1986

二唑丁酮安全信息

[ 符号 ]:

GHS07, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H410

[ 警示性声明 ]:
P301 + P312 + P330

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
60-61

[ 危险品运输编码 ]:
UN 3077

[ RTECS号 ]:
EL7085000

[ 海关编码 ]:
2933290012

二唑丁酮上下游产品

二唑丁酮上游产品

二唑丁酮下游产品

二唑丁酮海关

[ 海关编码 ]: 2933290012

[ 中文概述 ]:
2933290012 抑霉唑,咪菌腈,咪菌酮,咪鲜胺等〔包括克霉唑,咪鲜胺锰盐〕。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ 监管条件 ]: S.进出口农药登记证明

[ Summary ]:
2933290012 1-((2-chlorophenyl)diphenylmethyl)-1h-imidazole。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

二唑丁酮文献

Enhanced efficacy and sensory properties of an anti-dandruff shampoo containing zinc pyrithione and climbazole.

Int. J. Cosmet. Sci. 35(1) , 78-83, (2013)

Dandruff is a common complaint and is suffered by as much as half of the population at some time post puberty. The condition is characterized by the presence of flakes on the scalp and in the hair, an...

Efficacy of a piroctone olamine/climbazol shampoo in comparison with a zinc pyrithione shampoo in subjects with moderate to severe dandruff.

Int. J. Cosmet. Sci. 33(3) , 276-82, (2011)

Dandruff is a chronic scalp disorder characterized by scaling and itching. A successful anti-dandruff shampoo not only has to provide superior anti-dandruff relief to ensure patient compliance. It als...

[Determination of antidangdruff agent salicylic acid, zinc pyrithione, octopirox, climbazole and ketoconazole in shampoo by high performance liquid chromatography].

Wei Sheng Yan Jiu 34(5) , 626-8, (2005)

A high performance liquid chromatography method was established for determination of antidangdruff agent salicylic acid,zinc pyrithione, octopirox, climbazole and ketoconazole in shampoo on a C18 colu...

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