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5-乙烯基尿嘧啶

5-乙烯基尿嘧啶名称

[ CAS 号 ]:
37107-81-6

[ 中文名 ]:
5-乙烯尿嘧啶

[ 英文名 ]:
5-vinyluracil

[中文别名 ]:

[英文别名 ]:

5-ethenyluracil
5-vinyl-1H-pyrimidine-2,4-dione
MFCD00913267
5-ethenyl-2,4(1H,3H)-pyrimidinedione
5-Vinyl-uracil
5-ethenylpyrimidine-2,4-diol

5-乙烯基尿嘧啶物理化学性质

[ 密度 ]:
1.332g/cm3

[ 熔点 ]:
>300ºC (dec.)(lit.)

[ 分子式 ]:
C₆H₆N₂O₂

[ 分子量 ]:
138.12400

[ 精确质量 ]:
138.04300

[ PSA ]:
65.72000

[ 外观性状 ]:
Powder

[ 折射率 ]:
1.606

[ 储存条件 ]:
-20°C Freezer

5-乙烯基尿嘧啶安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-36/37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933599090

5-乙烯基尿嘧啶上下游产品

5-乙烯基尿嘧啶上游产品

5-乙烯基尿嘧啶下游产品

5-乙烯基尿嘧啶海关

[ 海关编码 ]: 2933599090

[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-乙烯基尿嘧啶文献

A method for the rapid preparation of 5-vinyluracil in high yield.

Nucleic Acids Res. 1(1) , 105-7, (1974)

A method for the rapid preparation of the thymineanalogue, 5-vinyluracil, in 83% yield from 5-(1-hydroxyethyl)uracil via the methanesulphonyl ester is reported.

Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.

Bioorg. Med. Chem. Lett. 13(5) , 867-72, (2003)

A series of tumor-activated prodrugs of the inhibitors of dihydropyrimidine dehydrogenase (DPD), an enzyme catabolizing 5-fluorouracil (5-FU: 4g), has been designed and synthesized. RO0094889 (11c) is...

Incorporation of 5-substituted uracil derivatives into nucleic acids. The isolation and gamma-radiation-sensitivity of bacteriophage T3 containing the thymine analogue 5-vinyluracil.

Biochem. J. 187(1) , 257-60, (1980)

Bacteriophage T3 was produced in a form that contained 32% of its normal DNA thymine residues replaced with 5-vinyluracil residues by infecting a thymine-requiring strain of Escherichia coli with phag...

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