N,N-二乙基羟胺(DEHA)

N,N-二乙基羟胺(DEHA)用途

【用途一】
用作乙烯基单体及共轭烯烃的高效阻聚剂，是丁苯乳聚过程的终止剂，是不饱和油类等的抗氧化剂
【用途二】
1、做为乙烯基单体，用于共轭烯烃的高效阻聚剂。2、在液相或气相中对已有端聚种子的情况下，可作为高效端聚抑制剂。3、是丁苯乳聚过程的非常优异的终止剂。4、是不饱和油类及树脂的抗氧化剂。5、是光敏树脂、感光乳剂、合成树脂的良好稳定剂。6、在环境保护中是良好的光化学烟雾抑制剂。7、是锅炉给水和蒸汽换热设备的缓蚀剂。

N,N-二乙基羟胺(DEHA)名称

[ CAS 号 ]:
3710-84-7

[ 中文名 ]:
二乙基羟胺

[ 英文名 ]:
N,N-Diethylhydroxylamine

[中文别名 ]:

[英文别名 ]:

N,N-Diethylhydroxylamine
pennstop,anhydrous
DEHA
pennstop
DIETHYL HYDROXYLAMINE
N-Hydroxydiethylamine
N-DiethylhydroxylaMine
[Ethyl(hydroxy)amino]ethan
ethylhydroxyethylamine
N-Ethyl-N-hydroxyethanamine

N,N-二乙基羟胺(DEHA)物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
133.0±0.0 °C at 760 mmHg

[ 熔点 ]:
−26-−25 °C(lit.)

[ 分子式 ]:
C₄H₁₁NO

[ 分子量 ]:
89.136

[ 闪点 ]:
45.0±0.0 °C

[ 精确质量 ]:
89.084061

[ PSA ]:
23.47000

[ LogP ]:
-0.09

[ 外观性状 ]:
淡黄色液体

[ 蒸汽密度 ]:
3.07 (vs air)

[ 蒸汽压 ]:
5.2±0.4 mmHg at 25°C

[ 折射率 ]:
1.433

[ 储存条件 ]:
Flammables area

[ 稳定性 ]:
Stable. Hygroscopic. Flammable. Incompatible with strong oxidizing agents, strong acids.

[ 水溶解性 ]:
soluble

N,N-二乙基羟胺(DEHA)MSDS

详细MSDS(安全技术说明书)

N,N-二乙基羟胺(DEHA)毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NC3500000

CHEMICAL NAME :: Hydroxylamine, N,N-diethyl-

CAS REGISTRY NUMBER :: 3710-84-7

BEILSTEIN REFERENCE NO. :: 1731349

LAST UPDATED :: 199712

DATA ITEMS CITED :: 18

MOLECULAR FORMULA :: C4-H11-N-O

MOLECULAR WEIGHT :: 89.16

WISWESSER LINE NOTATION :: QN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD80 - Lethal Dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 100 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 180 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 18 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 180 mg/kg

REFERENCE :: CAES** Reports Supported by the Pennwalt Corp. and the Center for Air Environment Studies at the Pennsylvania State University Volume(issue)/page/year: 492-78,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83719 No. of Facilities: 62 (estimated) No. of Industries: 1 No. of Occupations: 10 No. of Employees: 6533 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83719 No. of Facilities: 162 (estimated) No. of Industries: 5 No. of Occupations: 5 No. of Employees: 950 (estimated) No. of Female Employees: 14 (estimated)

N,N-二乙基羟胺(DEHA)安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H226-H312 + H332-H315-H319

[ 警示性声明 ]:
P280-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R10;R20/21;R36/37/38;R40

[ 安全声明 (欧洲) ]:
S36/37-S45-S36/37/39-S26-S16

[ 危险品运输编码 ]:
UN 1993 3/PG 3

[ WGK德国 ]:
1

[ RTECS号 ]:
NC3500000

[ 包装等级 ]:
III

[ 危险类别 ]:
3

[ 海关编码 ]:
2928000090

N,N-二乙基羟胺(DEHA)合成路线

详细合成路线

N,N-二乙基羟胺(DEHA)上下游产品

N,N-二乙基羟胺(DEHA)上游产品

N,N-二乙基羟胺(DEHA)下游产品

N,N-二乙基羟胺(DEHA)制备

1.在催化剂镉盐（CdCl2·2H2O）或锌盐（ZnCl2）存在下，以过氧化氢水溶液氧化仲胺，或在钛硅质岩催化剂存在下，以过氧化氢水溶液氧化二烷基胺（RRNH）或三乙胺均可制得本品。

2.在钛硅质岩催化剂的存在下，以过氧化氢氧化二烷基胺，制得二乙基羟胺。过氧化氢为30%的水溶液。钛硅质岩催化剂要研成细粉末。反应温度约80℃。操作时，先将催化剂和二烷基胺（如二乙基胺）置于反应器中，然后升温至80℃左右，并在搅拌下于35MIN内缓慢加入过氧化氢水溶液。产率可达87.1%。还可利用催化氧化硝酸灵（C2OH16N4）的方法制得二乙基羟胺。

3.1.制三乙胺氧化物
将0.094摩尔35%过氧化氢慢慢地加入0.032摩尔二乙胺溶于10毫升甲醇的冷溶液中，将反应液逐渐升温至室温并放置26小时。其时，胺的酚酞试验呈负结果。然后加入0.25i克铂黑并搅拌5小时以分解过量过氧化氢，其后过氧化氢试验为负结果，1滴反应液不能使硫化氢试纸变白.滤出铂黑，在减压下和浴温30一40℃浓缩滤液，得到无色粘稠浆状的三乙胺氧化物。

2.制N，N一二乙基经胺
将上述浆状三乙胺氧化物装入100毫升烧瓶，瓶上装有毛细氮气导入管和25厘米松针形分馏头，并通过空气冷凝器与三个串连的接受器相接，接受器依次用冰、干冰一丙酮和液氮冷。在通氮并减压至约20mm时，将烧瓶浸于油浴中，浴温慢慢升至120℃，猛烈地沸腾并有液体馏出。然后慢慢减至4mrn}浴温升较160℃以使热分解和蒸馏完全。从第一个接受器中收得N，N一二乙基经胺，产率69%，
方法二，搅拌下，将230份30%过氧化氢和60份甲酸乙醋同时滴入经冷却的160份二乙胺中，控制温度在55一60℃。反应完成后，加入浓盐酸，得到240份N，N一二乙基经胺盐酸盐，将盐酸盐碱化后，可得游离羟胺。

N,N-二乙基羟胺(DEHA)海关

[ 海关编码 ]: 2928000090

[ 中文概述 ]:
2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

N,N-二乙基羟胺(DEHA)文献

Hydrogen abstraction ability of different aromatic nitroxides.

Free Radic. Res. 38(1) , 67-72, (2004)

Indolinonic aromatic nitroxides have been shown to efficiently inhibit free radical mediated oxidation reactions in biological systems. Since all antioxidants also possess pro-oxidant activity, possib...

The effect of diethylhydroxylamine on the incidence of tumors induced by benzo(a)pyrene in the mouse.

Drug Chem. Toxicol. 7(4) , 315-27, (1984)

Groups of 20 male and 20 female CD-1(ICR)Br mice were treated either with 0, 3, 30, or 300 mg diethylhydroxylamine (DEHA)/kg-day (administered via the drinking water) from 57-112 days of age. For the ...

N,N-diethylhydroxylamine: a new electron donor to photosystem II.

Biochem. Biophys. Res. Commun. 179(2) , 1127-33, (1991)

Diethylhydroxylamine, when added to beet spinach thylakoid membranes in the reaction mixture enhanced both photosystem II mediated dichlorophenolindophenol photoreduction and whole chain electron tran...

更多文献