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L-蛋氨酸亚砜

L-蛋氨酸亚砜用途

L-Methionine sulfoxide (H-Met(O)-OH),甲硫氨酸的代谢产物,诱导 M1/classical 巨噬细胞极化,并调节氧化应激和嘌呤能的信号传递参数。

L-蛋氨酸亚砜名称

[ CAS 号 ]:
3226-65-1

[ 中文名 ]:
L-蛋氨酸亚砜

[ 英文名 ]:
H-Met(O)-OH

[中文别名 ]:

L-2-氨基-4-(甲基磺酰基)丁酸

[英文别名 ]:

Butanoic acid, 2-amino-4-(methylsulfinyl)-, (2S)-
EINECS 221-758-0
(2S)-2-Amino-4-(methylsulfinyl)butanoic acid
(3-Amino-3-carboxypropyl)(methyl)sulfoniumolate
2-Amino-4-(methylsulfinyl)butanoic acid
UNII:XN1XVI4B2C
MFCD00063093
L-methionine S-oxide
L-2-Amino-4-(methylsulfinyl)butanoic acid
Butanoic acid, 2-amino-4-(methylsulfinyl)-

L-蛋氨酸亚砜生物活性

[ 描述 ]:

L-Methionine sulfoxide (H-Met(O)-OH),甲硫氨酸的代谢产物,诱导 M1/classical 巨噬细胞极化,并调节氧化应激和嘌呤能的信号传递参数。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[参考文献]

[1]. Dos Santos LM, et al. Methionine and methionine sulfoxide treatment induces M1/classical macrophage polarization and modulates oxidative stress and purinergic signaling parameters. Mol Cell Biochem. 2017 Jan;424(1-2):69-78.

L-蛋氨酸亚砜物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
434.3±40.0 °C at 760 mmHg

[ 熔点 ]:
234-235ºC

[ 分子式 ]:
C₅H₁₁NO₃S

[ 分子量 ]:
165.211

[ 闪点 ]:
216.4±27.3 °C

[ 精确质量 ]:
165.045959

[ PSA ]:
99.60000

[ LogP ]:
-1.62

[ 外观性状 ]:
白色结晶固体

[ 蒸汽压 ]:
0.0±2.2 mmHg at 25°C

[ 折射率 ]:
1.570

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Temperature Sensitive, Hygroscopic

L-蛋氨酸亚砜MSDS

L-蛋氨酸亚砜安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2930909090

L-蛋氨酸亚砜合成路线

L-蛋氨酸亚砜上下游产品

L-蛋氨酸亚砜上游产品

L-蛋氨酸亚砜下游产品

L-蛋氨酸亚砜海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

L-蛋氨酸亚砜文献

Copper(II) complexes of neurokinin A with point mutation (S5A) and products of copper-catalyzed oxidation; role of serine residue in peptides containing neurokinin A sequence.

J. Inorg. Biochem. 121 , 1-9, (2013)

A potentiometric, spectroscopic (UV-visible, CD and EPR) and electrospray ionization mass spectrometric (ESI-MS) study of Cu(II) binding to the neurokinin A with point mutation (S5A) (ANKA), His-Lys-T...

Changes of metabolic profiles in an oral squamous cell carcinoma cell line induced by eugenol.

In Vivo 27(2) , 233-43, (2013)

We have recently reported that eugenol exerted indiscriminate cytotoxicity towards normal oral cells and oral squamous cell carcinoma (OSCC) cell lines without induction of apoptosis markers. In order...

Arrest defective 1 regulates the oxidative stress response in human cells and mice by acetylating methionine sulfoxide reductase A.

Cell Death Dis. 5 , e1490, (2014)

Methionine sulfoxide reductase A (MSRA) protects proteins from oxidation, and also helps remove reactive oxygen species (ROS) by recovering antioxidant enzymes inactivated by oxidation. Although its f...

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