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DL-蛋氨酸亚砜

DL-蛋氨酸亚砜用途

Methionine sulfoxide 是一种具有活性氧的甲硫氨酸的氧化产物,可被当做体内氧化应激的生物标记。

DL-蛋氨酸亚砜名称

[ CAS 号 ]:
62697-73-8

[ 中文名 ]:
DL-蛋氨酸亚砜

[ 英文名 ]:
Methionine sulfoxide

[英文别名 ]:

(3-Amino-3-carboxypropyl)(methyl)sulfoniumolate
2-Amino-4-(methylsulfinyl)butanoic acid
EINECS 263-700-7
2-Amino-4-(methylsulfinyl)butyric Acid
Butanoic acid, 2-amino-4-(methylsulfinyl)-
MFCD00002620
DL-METHIONINE SULFOXIDE
UNII:O74B4F6OYL

DL-蛋氨酸亚砜生物活性

[ 描述 ]:

Methionine sulfoxide 是一种具有活性氧的甲硫氨酸的氧化产物,可被当做体内氧化应激的生物标记。

[ 相关类别 ]:

研究领域 >> 代谢疾病

天然产物 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Mashima R, et al. Simultaneous determination of methionine sulfoxide and methionine in blood plasma using gas chromatography-mass spectrometry. Anal Biochem. 2003 Feb 1;313(1):28-33.

[相关活性小分子]

DL-蛋氨酸亚砜物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
434.3±40.0 °C at 760 mmHg

[ 熔点 ]:
240ºC

[ 分子式 ]:
C₅H₁₁NO₃S

[ 分子量 ]:
165.211

[ 闪点 ]:
216.4±27.3 °C

[ 精确质量 ]:
165.045959

[ PSA ]:
99.60000

[ LogP ]:
-1.62

[ 外观性状 ]:
固体;White to Light yellow to Light orange powder to crystal

[ 蒸汽压 ]:
0.0±2.2 mmHg at 25°C

[ 折射率 ]:
1.570

[ 储存条件 ]:
0-10°C;避免加热

[ 水溶解性 ]:
Soluble in water and Hcl.

DL-蛋氨酸亚砜MSDS

详细MSDS(安全技术说明书)

DL-蛋氨酸亚砜安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
ES7120000

DL-蛋氨酸亚砜文献

Copper(II) complexes of neurokinin A with point mutation (S5A) and products of copper-catalyzed oxidation; role of serine residue in peptides containing neurokinin A sequence.

J. Inorg. Biochem. 121 , 1-9, (2013)

A potentiometric, spectroscopic (UV-visible, CD and EPR) and electrospray ionization mass spectrometric (ESI-MS) study of Cu(II) binding to the neurokinin A with point mutation (S5A) (ANKA), His-Lys-T...

Changes of metabolic profiles in an oral squamous cell carcinoma cell line induced by eugenol.

In Vivo 27(2) , 233-43, (2013)

We have recently reported that eugenol exerted indiscriminate cytotoxicity towards normal oral cells and oral squamous cell carcinoma (OSCC) cell lines without induction of apoptosis markers. In order...

A sulfonium cation intermediate in the mechanism of methionine sulfoxide reductase B: a DFT study.

J. Phys. Chem. B 115(29) , 9202-12, (2011)

The hybrid density functional theory method B3LYP in combination with three systematically larger active site models has been used to investigate the substrate binding and catalytic mechanism by which...

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