3-二甲氨基-1-丙醇

3-二甲氨基-1-丙醇用途

【用途一】
用于医药原料，亦可作为纸张处理助剂、汽油添加剂等
【用途二】
用于生产中枢神经抑制药氯丙嗪、纸张处理助剂、汽油添加剂、树脂熟化剂等。3-二甲氨基-1-丙醇用氯化亚砜氯化可得1-氯-3-二甲氨基丙烷盐酸盐（[5407-04-5]）。将干燥的甲苯加入反应锅内，常温下开始滴加3-二甲氨基-1-丙醇和氯化亚砜，保持温度50-60℃。滴加完毕，缓缓升温至95-96℃，约需2h。反应结束后，冷却，分离，得1-氯-3-二甲氨基丙烷盐酸盐。
【用途三】
用于生产中枢神经抑制药氯丙嗪、纸张处理助剂、汽油添加剂、树脂熟化剂等。

3-二甲氨基-1-丙醇名称

[ CAS 号 ]:
3179-63-3

[ 中文名 ]:
3-二甲氨基-1-丙醇

[ 英文名 ]:
3-Dimethylaminopropanol

[中文别名 ]:

[英文别名 ]:

3-(Dimethylamino)Propan-1-Ol
3-Dimethylamino-1-propanol
1-Dimethylamino-3-propanol
MFCD00002945
3-(Dimethylamino)-1-propanol
γ-(Dimethylamino)propanol
3-N,N-dimethylaminopropan-1-ol
N,N-Dimethylpropanolamine
3-Dimethylaminopropanol
EINECS 221-659-2

3-二甲氨基-1-丙醇物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
163.5±0.0 °C at 760 mmHg

[ 熔点 ]:
-35 °C

[ 分子式 ]:
C₅H₁₃NO

[ 分子量 ]:
103.163

[ 闪点 ]:
36.1±0.0 °C

[ 精确质量 ]:
103.099716

[ PSA ]:
23.47000

[ LogP ]:
-0.49

[ 外观性状 ]:
透明至淡黄色液体

[ 蒸汽压 ]:
0.7±0.6 mmHg at 25°C

[ 折射率 ]:
1.439

[ 储存条件 ]:
库房通风低温干燥,与氧化剂,酸类分开储运

[ 稳定性 ]:
Stable. Flammable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
miscible

3-二甲氨基-1-丙醇MSDS

详细MSDS(安全技术说明书)

3-二甲氨基-1-丙醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB3155000

CHEMICAL NAME :: 1-Propanol, 3-(dimethylamino)-

CAS REGISTRY NUMBER :: 3179-63-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C5-H13-N-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2130 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (2),34,1996

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1650 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (2),34,1996

3-二甲氨基-1-丙醇安全信息

[ 符号 ]:

GHS02, GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H226-H318

[ 警示性声明 ]:
P280-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R10;R22;R34

[ 安全声明 (欧洲) ]:
S26-S39-S45-S36/37/39-S16

[ 危险品运输编码 ]:
UN 1987 3/PG 3

[ WGK德国 ]:
1

[ RTECS号 ]:
UB3155000

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
29221980

3-二甲氨基-1-丙醇合成路线

详细合成路线

3-二甲氨基-1-丙醇上下游产品

3-二甲氨基-1-丙醇上游产品

3-二甲氨基-1-丙醇下游产品

3-二甲氨基-1-丙醇制备

【方法一】
由丙烯醇与二甲胺在氢氧化钠存在下加成而得。

3-二甲氨基-1-丙醇海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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