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八甘醇单十二烷基醚

八甘醇单十二烷基醚用途

八乙二醇单十二烷基醚(C12E8)是一种可用于膜蛋白提取的非离子洗涤剂。八乙二醇单十二烷基醚可溶解完整流感病毒的病毒膜[1][2]。

八甘醇单十二烷基醚名称

[ CAS 号 ]:
3055-98-9

[ 中文名 ]:
辛乙烯二醇单正十二烷基酯

[ 英文名 ]:
Dodecyl octaethylene glycol ether

[中文别名 ]:

[英文别名 ]:

MFCD00043234
3,6,9,12,15,18,21,24-Octaoxahexatriacontan-1-ol
Dodecyloctaglycol
Polyoxyethylene (8) lauryl ether
Octaethylene Glycol Monododecyl Ether
octaoxyethylene glycol mono-n-dodecyl ether
n-dodecyl octaethylene glycol monoether
O-DODECANYL OCTAETHYLENE GLYCOL
octaethyleneglycol dodecyl ether
Dodecyl octaethylene glycol ether

八甘醇单十二烷基醚生物活性

[ 描述 ]:

八乙二醇单十二烷基醚(C12E8)是一种可用于膜蛋白提取的非离子洗涤剂。八乙二醇单十二烷基醚可溶解完整流感病毒的病毒膜[1][2]。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 流感病毒

研究领域 >> 感染

[体外研究]

八乙二醇单十二烷基醚(C12E8)可溶解完整流感病毒的病毒膜。病毒膜的增溶机制是基于C12E8分子在膜外聚集,直到形成胶束,从而提取膜成分[1]。

[参考文献]

[1]. Véronique Nardello-Rataj, et al. Aqueous solutions of didecyldimethylammonium chloride and octaethylene glycol monododecyl ether: Toward synergistic formulations against enveloped viruses. Int J Pharm. 2016 Sep 10;511(1):550-559.

[2]. C Carnero Ruiz, et al. Characterization of mixed non-ionic surfactants n-octyl-β-D-thioglucoside and octaethylene-glycol monododecyl ether: micellization and microstructure. J Colloid Interface Sci. 2011 Sep 1;361(1):178-85.

八甘醇单十二烷基醚物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
585.5±45.0 °C at 760 mmHg

[ 熔点 ]:
30ºC

[ 分子式 ]:
C₂₈H₅₈O₉

[ 分子量 ]:
538.755

[ 闪点 ]:
307.9±28.7 °C

[ 精确质量 ]:
538.408081

[ PSA ]:
94.07000

[ LogP ]:
2.54

[ 外观性状 ]:
无色固体

[ 蒸汽压 ]:
0.0±3.7 mmHg at 25°C

[ 折射率 ]:
1.459

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents. Combustible.

八甘醇单十二烷基醚MSDS

八甘醇单十二烷基醚安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2909499000

八甘醇单十二烷基醚合成路线

八甘醇单十二烷基醚上下游产品

八甘醇单十二烷基醚上游产品

八甘醇单十二烷基醚下游产品

八甘醇单十二烷基醚海关

[ 海关编码 ]: 2909499000

[ 中文概述 ]:
2909499000 其他醚醇及其卤化、磺化、硝化或亚硝化衍生物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

八甘醇单十二烷基醚文献

Folding and Intramembraneous BRICHOS Binding of the Prosurfactant Protein C Transmembrane Segment.

J. Biol. Chem. 290 , 17628-41, (2015)

Surfactant protein C (SP-C) is a novel amyloid protein found in the lung tissue of patients suffering from interstitial lung disease (ILD) due to mutations in the gene of the precursor protein pro-SP-...

Molecular and biochemical characterisation of human short-chain dehydrogenase/reductase member 3 (DHRS3)

Chem. Biol. Interact. 234 , 178-87, (2015)

• DHRS3 is an integral membrane protein with its C-terminus in the cytosol. • Androstenedione and estrone are substrates of DHRS3 in vitro. • DHRS3 was inserted into proteoliposomes. • Expression of D...

Octadecyl ferulate behavior in 1,2-Dioleoylphosphocholine liposomes.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 153 , 333-43, (2015)

Octadecyl ferulate was prepared using solid acid catalyst, monitored using Supercritical Fluid Chromatography and purified to a 42% yield. Differential scanning calorimetry measurements determined oct...

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