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4-硝基-DL-苯丙氨酸

4-硝基-DL-苯丙氨酸用途

H-DL-Phe(4-NO2)-OH是苯丙氨酸衍生物[1]。

4-硝基-DL-苯丙氨酸名称

[ CAS 号 ]:
2922-40-9

[ 中文名 ]:
4-硝基-DL-苯丙氨酸

[ 英文名 ]:
L-4-Nitrophenylalanine

[中文别名 ]:

DL-对硝基苯丙氨酸一水

[英文别名 ]:

2-Amino-3-(4-nitrophenyl)propanoic acid
4-nitro-DL-phenylalanine
L-4-Nitrophe
4-Nitrophenylalanine
para-nitrophenylalanine
L-Phenylalanine, 4-nitro- (9CI)
p-Nitrophenylalanine
L-Phenylalanine, 4-nitro-
Nitrophenylalanine
4-14-00-01677 (Beilstein Handbook Reference)

4-硝基-DL-苯丙氨酸生物活性

[ 描述 ]:

H-DL-Phe(4-NO2)-OH是苯丙氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-824.

4-硝基-DL-苯丙氨酸物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
414.1±35.0 °C at 760 mmHg

[ 熔点 ]:
236-237 °C (dec.)(lit.)

[ 分子式 ]:
C₉H₁₀N₂O₄

[ 分子量 ]:
210.187

[ 闪点 ]:
204.2±25.9 °C

[ 精确质量 ]:
210.064056

[ PSA ]:
109.14000

[ LogP ]:
0.84

[ 外观性状 ]:
米色粉末

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.614

[ 储存条件 ]:
Store at RT.

4-硝基-DL-苯丙氨酸MSDS

详细MSDS(安全技术说明书)

4-硝基-DL-苯丙氨酸安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301

[ 警示性声明 ]:
P301 + P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T: Toxic;

[ 风险声明 (欧洲) ]:
R25

[ 安全声明 (欧洲) ]:
S45

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

[ 危险类别 ]:
6.1

4-硝基-DL-苯丙氨酸文献

Sensitive, soluble chromogenic substrates for HIV-1 proteinase.

J. Biol. Chem. 265 , 7733, (1990)

By replacement of the P1' residue in a capsid/nucleocapsid cleavage site mimic with 4-NO2-phenylalanine (Nph), an excellent chromogenic substrate, Lys-Ala-Arg-Val-Leu*Nph-Glu-Ala-Met, for HIV-1 protei...

Genetic incorporation of unnatural amino acids into proteins in Mycobacterium tuberculosis.

PLoS ONE 5(2) , e9354, (2010)

New tools are needed to study the intracellular pathogen Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), to facilitate new drug discovery and vaccine development. We have d...

Comparison of fluorescence reagents for simultaneous determination of hydroxylated phenylalanine and nitrated tyrosine by high-performance liquid chromatography with fluorescence detection.

Biomed. Chromatogr. 26(1) , 41-50, (2012)

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are well-known and important contributors to oxidative and nitrosative stress in several diseases. Hydroxylated phenylalanine and nitr...

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