5-[5-[(Z)-[1-(3-carboxyphenyl)-3-methyl-5-oxopyrazol-4-ylidene]methyl]furan-2-yl]-2-chlorobenzoic acid

TDRL-X80是着色性干皮病a组(XPA)蛋白的有效抑制剂。TDRL-X80抑制XPA的DNA结合活性。TDRL-X80在荧光偏振(FP)分析中的IC50s为18、20和29μM,在ELISA分析中的IC50s为21、39和28,显示出对抗单、双和顺铂损伤DNA的活性【1】。

[ 描述 ]:

[ 相关类别 ]:

[参考文献]

[ 分子式 ]:
C₂₃H₁₅ClN₂O₆

[ 分子量 ]:
450.82800

[ 精确质量 ]:
450.06200

[ PSA ]:
120.41000

[ LogP ]:
4.30310

详细MSDS(安全技术说明书)

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H413

[ 危险品运输编码 ]:
NONH for all modes of transport

Biochemistry and Cell Wall Changes Associated with Noni (Morinda citrifolia L.) Fruit Ripening.

J. Agric. Food Chem. 64 , 302-9, (2016)

Quality and compositional changes were determined in noni fruit harvested at five ripening stages, from dark-green to thaslucent-grayish. Fruit ripening was accompanied by acidity and soluble solids a...

Race/ethnicity and potential suicide misclassification: window on a minority suicide paradox?

BMC Psychiatry 10 , 35, (2010)

Suicide officially kills approximately 30,000 annually in the United States. Analysis of this leading public health problem is complicated by undercounting. Despite persisting socioeconomic and health...

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