2,4-滴钠盐

2,4-滴钠盐用途

2,4-D sodium salt (Sodium 2,4-dichlorophenoxyacetate) 是一种用于阔叶杂草防治的选择性除草剂。2,4-D sodium salt 作为一种植物激素,在分生组织中引起不受控制的生长。2,4-D sodium salt 抑制 DNA 和蛋白质的合成,从而阻止植物的正常生长发育。

2,4-滴钠盐名称

[ CAS 号 ]:
2702-72-9

[ 中文名 ]:
2,4-滴钠盐

[ 英文名 ]:
2,4-D sodium salt

[中文别名 ]:

[英文别名 ]:

sodium 2-(2,4-dichlorophenoxy)acetate
2,4-D sodium salt
Fernoxene
dikonirtd
pielike
2,4,6-TMPAC (MESITY ACETI ACID)
Pielik E
Sodium 2,4-D
Sodium 2,4-dichlorophenoxyacetate
U-46-D-Fluid

2,4-滴钠盐生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 细胞周期/DNA损伤 >> DNA/RNA合成

研究领域 >> 其他

[参考文献]

[1]. Germaine KJ, et al. Bacterial endophyte-enhanced phytoremediation of the organochlorine herbicide 2,4-dichlorophenoxyacetic acid. FEMS Microbiol Ecol. 2006 Aug;57(2):302-10.

2,4-滴钠盐物理化学性质

[ 沸点 ]:
345.6ºC at 760 mmHg

[ 熔点 ]:
215°C

[ 分子式 ]:
C₈H₅Cl₂NaO₃

[ 分子量 ]:
243.019

[ 闪点 ]:
162.8ºC

[ 精确质量 ]:
241.951340

[ PSA ]:
49.36000

[ LogP ]:
1.12210

[ 外观性状 ]:
透明棕色至黑色液体

[ 蒸汽压 ]:
2.31E-05mmHg at 25°C

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

[ 水溶解性 ]:
Soluble

2,4-滴钠盐MSDS

2,4-滴钠盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AG8925000

CHEMICAL NAME :: Acetic acid, (2,4-dichlorophenoxy)-, sodium salt

CAS REGISTRY NUMBER :: 2702-72-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 23

MOLECULAR FORMULA :: C8-H5-Cl2-O3.Na

MOLECULAR WEIGHT :: 243.02

WISWESSER LINE NOTATION :: OV1OR BG DG &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 23 mg/m3/3Y-I

TOXIC EFFECTS :: Behavioral - anorexia (human) Gastrointestinal - other changes Liver - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 555 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 424 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 375 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - ataxia Behavioral - coma

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 375 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - ataxia Behavioral - coma

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Behavioral - stiffness Behavioral - coma

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - ataxia Behavioral - coma

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - ataxia Behavioral - coma

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Cardiac - EKG changes not diagnostic of specified effects

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - ataxia Behavioral - coma

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 666 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - ataxia Behavioral - coma

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 59500 mg/kg/17W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - proteinuria Blood - normocytic anemia Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6300 mg/kg/12W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - other changes in urine composition Blood - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 100 ug/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Bird - chicken Cells - not otherwise specified

DOSE/DURATION :: 2500 umol/L

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 33,91,1975 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

2,4-滴钠盐安全信息

[ 危害码 (欧洲) ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R22;R41;R43;R51/53

[ 安全声明 (欧洲) ]:
S24/25-S26-S36/37/39-S46-S61

[ 危险品运输编码 ]:
UN 3077 9/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
AG8925000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2918990090

2,4-滴钠盐合成路线

2,4-滴钠盐上下游产品

2,4-滴钠盐上游产品

2,4-滴钠盐下游产品

2,4-滴钠盐海关

[ 海关编码 ]: 2918990090

[ 中文概述 ]:
2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%