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溶剂橙2

溶剂橙2用途

C.I. Solvent Orange 2 is a dye.

溶剂橙2名称

[ CAS 号 ]:
2646-17-5

[ 中文名 ]:
溶剂橙 2

[ 英文名 ]:
C.I. Solvent Orange 2

[中文别名 ]:

[英文别名 ]:

ORANGE OT
Oil Orange SS
1-(o-Tolylazo)-2-naphthol
toluene-<2 azo 1>-2-naphthol
orangess
fatorangeii
Orange RC
oranzss
oilorangeot
MFCD00059523

溶剂橙2物理化学性质

[ 密度 ]:
1.15 g/cm3

[ 沸点 ]:
464.9ºC at 760 mmHg

[ 熔点 ]:
124-126°C

[ 分子式 ]:
C₁₇H₁₄N₂O

[ 分子量 ]:
262.30600

[ 闪点 ]:
306.4ºC

[ 精确质量 ]:
262.11100

[ PSA ]:
44.95000

[ LogP ]:
5.26920

[ 外观性状 ]:
红色针状或粉末

[ 蒸汽压 ]:
3.34E-07mmHg at 25°C

[ 折射率 ]:
1.624

[ 储存条件 ]:
室温

[ 水溶解性 ]:
水溶性：不溶；微溶：氯仿,丙酮,苯,乙醇

溶剂橙2MSDS

详细MSDS(安全技术说明书)

溶剂橙2毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL5425000

CHEMICAL NAME :: 2-Naphthol, 1-(o-tolylazo)-

CAS REGISTRY NUMBER :: 2646-17-5

BEILSTEIN REFERENCE NO. :: 0959684

LAST UPDATED :: 199709

DATA ITEMS CITED :: 18

MOLECULAR FORMULA :: C17-H14-N2-O

MOLECULAR WEIGHT :: 262.33

WISWESSER LINE NOTATION :: L66J BNUNR B1& CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - food intake (animal) Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - changes in structure or function of salivary glands

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Behavioral - food intake (animal) Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - changes in structure or function of salivary glands

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 56 gm/kg/20W-I

TOXIC EFFECTS :: Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - changes in testicular weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 115 gm/kg/44W-C

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6 gm/kg/52W

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg/48H (Intermittent)

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 389,3,1997 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,165,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,165,1975 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW ARVPAX Annual Review of Pharmacology. (Palo Alto, CA) V.1-15, 1961-75. For publisher information, see ARPTDI. Volume(issue)/page/year: 14,127,1974 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971

溶剂橙2安全信息

[ 符号 ]:

GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H351

[ 警示性声明 ]:
P281

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R40

[ 安全声明 (欧洲) ]:
S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
QL5425000

[ 海关编码 ]:
2928000090

溶剂橙2上下游产品

溶剂橙2上游产品

溶剂橙2下游产品

溶剂橙2海关

[ 海关编码 ]: 2928000090

[ 中文概述 ]:
2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

溶剂橙2文献

Furoquinoline alkaloids as photosensitizers in Chlamydomonas reinhardtii.

Mutat. Res. 249(1) , 105-10, (1991)

Seven naturally occurring furoquinoline alkaloids were investigated for their photobiological activity using arg-1 cells of Chlamydomonas reinhardtii. UV-A-mediated toxicity of the compounds was calcu...

Effect of 1-m-tolueneazo-2-naphthol on hepatic drug metabolism. I. Induction of cytochrome P-448.

J. Pharmacobiodyn. 5(4) , 259-65, (1982)

Treatment of rats with 1-m-tolueneazo-2-naphthol (mTAN) caused marked increase in liver weight, microsomal 7-ethoxycoumarin O-deethylase activity and cytochrome P-450 content, with 2 nm hypochromic sh...

The effect of tyrosine conjugation on the critical micellar concentration of free and glycine-conjugated bile salts.

Biochim. Biophys. Acta 876(3) , 677-83, (1986)

We investigated the effect of conjugation with the aromatic amino acid tyrosine on the critical micellar concentration (CMC) of bile salts. The CMC values were determined by surface tension and by dye...

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