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(+)-尼古丁

(+)-尼古丁名称

[ CAS 号 ]:
25162-00-9

[ 中文名 ]:
(+)-尼古丁

[ 英文名 ]:
(+)-Nicotine

[英文别名 ]:

Leukotriene B4 Lipid Maps MS Standard
leukotriene B4 ethanol solution
R-(+)-Nicotine
Leukotriene B4
6Z,8E,10E,14Z,5S,12R-diHETE
LTB4

(+)-尼古丁物理化学性质

[ 密度 ]:
1.032g/cm3

[ 沸点 ]:
244.4ºC at 760mmHg

[ 分子式 ]:
C₁₀H₁₄N₂

[ 分子量 ]:
162.23200

[ 闪点 ]:
101.7ºC

[ 精确质量 ]:
162.11600

[ PSA ]:
16.13000

[ LogP ]:
1.78620

[ 储存条件 ]:
-20°C

(+)-尼古丁毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QS5260000

CHEMICAL NAME :: 2'-beta-H-Nicotine

CAS REGISTRY NUMBER :: 25162-00-9

BEILSTEIN REFERENCE NO. :: 4666243

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H14-N2

MOLECULAR WEIGHT :: 162.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Cardiac - pulse rate Vascular - BP elevation not characterized in autonomic section

REFERENCE :: 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,584,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6150 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 84,1,1984

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Cardiac - pulse rate Vascular - BP elevation not characterized in autonomic section

REFERENCE :: 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,584,1948

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Bird - domestic

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHZOA9 Physiological Zoology. (Univ. of Chicago Press, Journals Div., POB 37005, Chicago, IL 60637) V.1- 1928- Volume(issue)/page/year: 12,238,1939

(+)-尼古丁安全信息

[ 危害码 (欧洲) ]:
Xi

[ 海关编码 ]:
2933990090

(+)-尼古丁合成路线

详细合成路线

(+)-尼古丁上下游产品

(+)-尼古丁上游产品

(+)-尼古丁下游产品

(+)-尼古丁海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%