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反,反-2,4-癸二烯醛

反,反-2,4-癸二烯醛用途

反式,反式-2,4-癸二烯醛是亚油酸的脂质过氧化产物[1]。

反,反-2,4-癸二烯醛名称

[ CAS 号 ]:
25152-84-5

[ 中文名 ]:
反式-2,4-癸二烯醛

[ 英文名 ]:
(2E,4E)-Deca-2,4-dienal

[中文别名 ]:

[英文别名 ]:

DDA
FEMA 3135
DECADIENEALDEHYDE
(2E,4E)-2,4-Decadienal
2,4-Decadienal, (2E,4E)-
2E,4E-DECADIENAL
2,4-Decadienal
(2E,4E)-Deca-2,4-dienal
trans,trans-2,4-Decadienal
2,4-DECADIEN-1-AL

反,反-2,4-癸二烯醛生物活性

[ 描述 ]:

反式,反式-2,4-癸二烯醛是亚油酸的脂质过氧化产物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

提出了两种体内生物转化反式,反式-2,4-癸二烯醛(tt-DDE)的代谢途径：(i)tt-DDE在肝细胞中氧化为相应的羧酸,2,4-癸二烯酸和(ii)谷胱甘肽(GHS)结合、GSH分解和醛还原,在肝细胞和肺细胞中产生半胱氨酸结合的2,4-癸二烯-1-醇。

[参考文献]

[1]. Kao-Lu Pan, et al. Identification of trans,trans-2,4-decadienal metabolites in mouse and human cells using liquid chromatography-mass spectrometry. Chem Res Toxicol. 2014 Oct 20;27(10):1707-19.

反,反-2,4-癸二烯醛物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
244.6±0.0 °C at 760 mmHg

[ 分子式 ]:
C₁₀H₁₆O

[ 分子量 ]:
152.233

[ 闪点 ]:
102.3±11.0 °C

[ 精确质量 ]:
152.120117

[ PSA ]:
17.07000

[ LogP ]:
3.18

[ 外观性状 ]:
透明黄色液体

[ 蒸汽密度 ]:
>1 (vs air)

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.459

[ 储存条件 ]:
Refrigerator (+4°C)

[ 水溶解性 ]:
insoluble

反,反-2,4-癸二烯醛MSDS

反,反-2,4-癸二烯醛毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HD3000000

CHEMICAL NAME :: 2,4-Decadienal, (E,E)-

CAS REGISTRY NUMBER :: 25152-84-5

BEILSTEIN REFERENCE NO. :: 1704897

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H16-O

MOLECULAR WEIGHT :: 152.26

反,反-2,4-癸二烯醛安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
HD3000000

[ 包装等级 ]:
III

反,反-2,4-癸二烯醛合成路线

反,反-2,4-癸二烯醛上下游产品

反,反-2,4-癸二烯醛上游产品

反,反-2,4-癸二烯醛下游产品

反,反-2,4-癸二烯醛制备

在亚油酸甲酯氢过氧化物(反一反式体)的自动氧化过程中形成

反,反-2,4-癸二烯醛文献

Olfactometry Profiles and Quantitation of Volatile Sulfur Compounds of Swiss Tilsit Cheeses.

J. Agric. Food Chem. 63 , 7511-21, (2015)

To establish the odor profiles of three differently fabricated commercial Swiss Tilsit cheeses, analyses were conducted using headspace solid-phase microextraction gas chromatography-mass spectrometry...

Characterization of Volatile Flavor Compounds in Chinese Rice Wine Fermented from Enzymatic Extruded Rice.

J. Food Sci. 80 , C1476-89, (2015)

Enzymatic extrusion, instead of traditional steam cooking, to treat rice is an efficient and alternative pretreatment for Chinese rice wine fermentation. In order to determine the formation of volatil...

trans,trans-2,4-decadienal induces mitochondrial dysfunction and oxidative stress.

J. Bioenerg. Biomembr. 40(2) , 103-9, (2008)

Lipid peroxidation produces a large number of reactive aldehydes as secondary products. We have previously shown that the reaction of cytochrome c with trans,trans-2,4-decadienal (DDE), an aldehyde ge...

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