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双去氧基姜黄素

双去氧基姜黄素用途

双脱甲氧基cucurmin(p,p’-二羟基二氰胺基甲烷)是一种姜黄素,具有抗氧化和抗炎活性[1][2]。

双去氧基姜黄素名称

[ CAS 号 ]:
24939-16-0

[ 中文名 ]:
双去甲氧基姜黄素

[ 英文名 ]:
Bisdemethoxycurcumin

[中文别名 ]:

双去氧基姜黄素

[英文别名 ]:

DEMETHOXYCURCUMIN,BIS
Bis(p-hydroxycinnamoyl)methane
Bisdemethoxycurcumin
1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
p,p'-Dihydroxydicinnamoylmethane
CURCUMIN 3
bis demethoxycurcumin
Bisdemethoxycucurmin
bisdemetoxycurcumin
curcumin III

双去氧基姜黄素生物活性

[ 描述 ]:

双脱甲氧基cucurmin(p,p’-二羟基二氰胺基甲烷)是一种姜黄素,具有抗氧化和抗炎活性[1][2]。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[参考文献]

[1]. M Kuroyanagi, et al. [Some observation on curcuminoids from Zingiberaceae plants]. Yakugaku Zasshi. 1970 Nov;90(11):1467-70.

[2]. Toshiya Masuda, et al. Antioxidative and Antiinflammatory Compounds from Tropical Gingers: Isolation, Structure Determination, and Activities of Cassumunins A, B, and C, New Complex Curcuminoids from Zingiber cassumunar. J. Agric. Food Chem. 1994, 42, 9, 1850–1856

双去氧基姜黄素物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
551.3±45.0 °C at 760 mmHg

[ 熔点 ]:
91-93℃

[ 分子式 ]:
C₁₉H₁₆O₄

[ 分子量 ]:
308.328

[ 闪点 ]:
301.3±25.2 °C

[ 精确质量 ]:
308.104858

[ PSA ]:
74.60000

[ LogP ]:
3.39

[ 外观性状 ]:
固体;Light yellow to Brown powder to crystal

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.680

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
DMSO: ≥20mg/mL

双去氧基姜黄素MSDS

详细MSDS(安全技术说明书)

双去氧基姜黄素安全信息

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2914501900

双去氧基姜黄素海关

[ 海关编码 ]: 2914501900

[ 中文概述 ]:
2914501900 其他酮酚。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

双去氧基姜黄素文献

Bis-demethoxy curcumin analog nanoparticles: synthesis, characterization, and anticancer activity in vitro.

J. Nanosci. Nanotechnol. 14(7) , 4865-73, (2014)

We have optimized a protocol for the preparation of bisdemethoxy curcumin analog nanoparticles (BDMCA-NP) by the solvent assisted process. The structural similarities between bulk and nano BDMCA were ...

Therapeutic potential of turmeric in Alzheimer's disease: curcumin or curcuminoids?

Phytother Res. 28(4) , 517-25, (2014)

Alzheimer's disease (AD) is the most common form of dementia. There is limited choice in modern therapeutics, and drugs available have limited success with multiple side effects in addition to high co...

Differential cellular uptake and metabolism of curcuminoids in monocytes/macrophages: regulatory effects on lipid accumulation.

Br. J. Nutr. 112(1) , 8-14, (2014)

We have previously shown that curcumin (CUR) may increase lipid accumulation in cultured human acute monocytic leukaemia cell line THP-1 monocytes/macrophages, but that tetrahydrocurcumin (THC), an in...

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