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1-乙酰基咪唑

1-乙酰基咪唑用途

【用途一】
用作医药中间体
【用途二】
作乙酰化试剂，供生化研究用。

1-乙酰基咪唑名称

[ CAS 号 ]:
2466-76-4

[ 中文名 ]:
1-乙酰基咪唑

[ 英文名 ]:
1-acetylimidazole

[中文别名 ]:

[英文别名 ]:

MFCD00005287
N-Acetylimidazole
1-Acetyl-1H-imidazole
Ethanone, 1-(1H-imidazol-1-yl)-
EINECS 219-577-7
1-(1H-Imidazol-1-yl)ethanone
Acetylimidazole
1-acetylimidazole
IMIDAZOLE,1-ACETYL
1H-Imidazole,1-acetyl

1-乙酰基咪唑物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
222.0±23.0 °C at 760 mmHg

[ 熔点 ]:
99-105 °C(lit.)

[ 分子式 ]:
C₅H₆N₂O

[ 分子量 ]:
110.114

[ 闪点 ]:
88.0±22.6 °C

[ 精确质量 ]:
110.048012

[ PSA ]:
34.89000

[ LogP ]:
-0.34

[ 外观性状 ]:
白色至淡黄色晶体

[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C

[ 折射率 ]:
1.552

[ 储存条件 ]:
库房通风低温干燥

1-乙酰基咪唑MSDS

详细MSDS(安全技术说明书)

1-乙酰基咪唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI3400000

CHEMICAL NAME :: Imidazole, 1-acetyl-

CAS REGISTRY NUMBER :: 2466-76-4

BEILSTEIN REFERENCE NO. :: 0108425

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C5-H6-N2-O

MOLECULAR WEIGHT :: 110.13

WISWESSER LINE NOTATION :: T5N CNJ AV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Immunological Including Allergic - decreased immune response

REFERENCE :: StoGD# Personal Communication from G.D. Stoner, Dept. of Community Medicine, School of Medicine, Univ. of California, La Jolla, CA 92037, May 25, 1975 Volume(issue)/page/year: 27MAY1975 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg/I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 54,495,1975

1-乙酰基咪唑安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
NI3400000

[ 海关编码 ]:
2933290090

1-乙酰基咪唑上下游产品

1-乙酰基咪唑上游产品

1-乙酰基咪唑下游产品

1-乙酰基咪唑制备

1.咪唑与乙酸异丙烯酯反应在50毫升圆烧瓶中，加入0.2g(0.03mol)咪唑，20ml乙酸异丙烯酯和几滴浓硫酸。将混合物在60℃保温1h。蒸馏除去少量的乙酸异丙烯酯和丙酮。剩余物用水碳酸钠处理。倾出液体。在空气浴中蒸发至干。得粗品3.1g，产率94%，熔点93-96℃。现经乙酸异丙烯酯重结晶，熔点达到101.5102.5℃。

1-乙酰基咪唑海关

[ 海关编码 ]: 2933290090

[ 中文概述 ]:
2933290090. 其他结构含非稠合咪唑环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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