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左美诺醇

左美诺醇用途

Levomenol 是一种单环倍半萜醇,存在于各种植物中,主要存在于洋甘菊中,具有抗氧化、抗炎和抗凋亡的作用。Levomenol 具有神经保护作用,在三叉神经性疼痛的啮齿动物模型中可以减弱伤害行为和中枢敏感性。

左美诺醇名称

[ CAS 号 ]:
23089-26-1

[ 中文名 ]:
(-)-α-红没药醇

[ 英文名 ]:
levomenol

[中文别名 ]:

左美诺醇

[英文别名 ]:

(-)-a-Bisabolol
(-)-α-Bisabolol
MFCD03412455
l-a-Bisabolol
Levomenlol
levomenol
EINECS 245-423-3
α-Bisabolol (-)-form
Bisbalol
(-)-(1'S,2S)-a-Bisabolol

左美诺醇生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 细胞凋亡 >> 细胞凋亡

研究领域 >> 炎症/免疫

研究领域 >> 神经疾病

[参考文献]

[1]. Fernandes MYD, et al. (-)-α-bisabolol prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice. Eur J Pharmacol. 2019 Jan 5;842:270-280.

[2]. Melo LT, et al. (-)-α-Bisabolol reduces nociception and trigeminal central sensitisation in acute orofacial neuropathic pain induced by infraorbital nerve injury. Life Sci. 2019 Jun 15;227:122-128.

左美诺醇物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
314.5±11.0 °C at 760 mmHg

[ 分子式 ]:
C₁₅H₂₆O

[ 分子量 ]:
222.366

[ 闪点 ]:
113.2±15.6 °C

[ 精确质量 ]:
222.198364

[ PSA ]:
20.23000

[ LogP ]:
5.07

[ 外观性状 ]:
透明至淡黄色液体

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.494

[ 储存条件 ]:
?20°C

左美诺醇MSDS

详细MSDS(安全技术说明书)

左美诺醇安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
MJ9685000

左美诺醇文献

The antimicrobial activity of alpha-bisabolol and tea tree oil against Solobacterium moorei, a Gram-positive bacterium associated with halitosis.

Arch. Oral Biol. 58(1) , 10-6, (2013)

To investigate the antimicrobial effect of alpha-bisabolol and tea tree oil alone and in combination against the halitosis-associated Gram-positive bacillus Solobacterium moorei.The inhibitory activit...

Antitumor effects of α-bisabolol against pancreatic cancer.

Cancer Sci. 102(12) , 2199-205, (2011)

In the present study, we investigated whether α-bisabolol, a sesquiterpene alcohol present in essential oils derived from a variety of plants, has antitumor effects against pancreatic cancer. α-Bisabo...

In vitro and in vivo antimalarial activity of essential oils and chemical components from three medicinal plants found in northeastern Brazil.

Planta Med. 78(7) , 658-64, (2012)

The prophylactic and therapeutic arsenal against malaria is quite restricted and all the antimalarials currently in use have limitations. Thus, there is a need to investigate medicinal plants in the s...

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