Cholesterol 24-hydroxylase-IN-2

Cholesterol 24-hydroxylase-IN-2用途

Cholesterol 24-Hydroxylase-IN-2 是胆固醇 24-羟化酶(CH24H 或 CYP46A1)的抑制剂,IC50 为 5.4 nM。胆固醇 24-羟化酶-IN-2 可用于哺乳动物胆固醇 24-羟化酶的成像。

Cholesterol 24-hydroxylase-IN-2名称

[ CAS 号 ]:
1613481-52-9

[ 英文名 ]:
Cholesterol 24-hydroxylase-IN-2

Cholesterol 24-hydroxylase-IN-2生物活性

[ 描述 ]:

Cholesterol 24-Hydroxylase-IN-2 是胆固醇 24-羟化酶(CH24H 或 CYP46A1)的抑制剂,IC50 为 5.4 nM。胆固醇 24-羟化酶-IN-2 可用于哺乳动物胆固醇 24-羟化酶的成像。

[ 相关类别 ]:

信号通路 >> 代谢酶/蛋白酶 >> 细胞色素P450

研究领域 >> 其他

[参考文献]

[1]. Koike Tatsuki, et al. Preparation of arylpiperidines and arylpiperazines as radiolabeled compounds for use in imaging of cholesterol 24-hydroxylase. World Intellectual Property Organization, WO2015190613 A1 2015-12-17

Cholesterol 24-hydroxylase-IN-2物理化学性质

[ 分子式 ]:
C₂₀H₂₃FN₄O

[ 分子量 ]:
354.42

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相关化合物

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标题：【Cholesterol 24-hydroxylase-IN-2】Cholesterol 24-hydroxylase-IN-2 CAS号:1613481-52-9【结构式性质活性】-化源网地址：https://www.chemsrc.com/amp/cas/1613481-52-9_1815796.html