烟丙法宗
烟丙法宗名称
[ CAS 号 ]:
15387-10-7
[ 中文名 ]:
烟丙法宗
[ 英文名 ]:
N-[[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-propan-2-ylamino]methyl]pyridine-3-carboxamide
[英文别名 ]:
- Ra 101 (pharmaceutical)
- Niprofazonum [INN-Latin]
- Nicotinamide,N-((antipyrinylisopropylamino)methyl)
- Nicotinamidomethylaminopyrazolone
- Niprofazona [INN-Spanish]
- Niprofazone
- RA 101
- N-((Antipyrinylisopropylamino)methyl)nicotinamide
烟丙法宗物理化学性质
[ 密度 ]:
1.25g/cm3
[ 分子式 ]:
C21H25N5O2
[ 分子量 ]:
379.45600
[ 精确质量 ]:
379.20100
[ PSA ]:
72.16000
[ LogP ]:
2.87260
[ 折射率 ]:
1.638
[ 储存条件 ]:
库房通风低温干燥
烟丙法宗毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QS4025000
- CHEMICAL NAME :
- Nicotinamide, N-((antipyrinylisopropylamino)methyl)-
- CAS REGISTRY NUMBER :
- 15387-10-7
- BEILSTEIN REFERENCE NO. :
- 0766712
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C21-H25-N5-O2
- MOLECULAR WEIGHT :
- 379.51
- WISWESSER LINE NOTATION :
- T6NJ CVM1NY1&1&- DT5NNVJ A1 BR& E1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1460 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1060 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 853 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970
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