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Morphinan, 3-methoxy

Morphinan, 3-methoxy名称

[ CAS 号 ]:
1531-25-5

[ 英文名 ]:
Morphinan, 3-methoxy

[英文别名 ]:

3-methoxymorphinan
(9S,13S,14S)-(+)-3-methoxymorphinan
N-nordextromethorphan

Morphinan, 3-methoxy物理化学性质

[ 密度 ]:
1.12g/cm3

[ 沸点 ]:
403.2ºC at 760mmHg

[ 分子式 ]:
C₁₇H₂₃NO

[ 分子量 ]:
257.37100

[ 闪点 ]:
167.1ºC

[ 精确质量 ]:
257.17800

[ PSA ]:
21.26000

[ LogP ]:
3.37000

[ 蒸汽压 ]:
0mmHg at 25°C

[ 折射率 ]:
1.587

Morphinan, 3-methoxy安全信息

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

Morphinan, 3-methoxy文献

A validated SIM GC/MS method for the simultaneous determination of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in biological matrices and its application to in vitro CYP2D6 and CYP3A4 inhibition study.

Biomed. Chromatogr. 23(11) , 1131-7, (2009)

Dextromethorphan is used as a probe drug for assessing CYP2D6 and CYP3A4 activity in vivo and in vitro. A SIM GC/MS method without derivatization for the simultaneous determination of dextromethorphan...

Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry.

J. Pharm. Biomed. Anal. 54(2) , 387-94, (2011)

A rapid and sensitive ultra performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) method has been developed and validated for the simultaneous quantitative determination of dextromet...

Effect of black seed on dextromethorphan O- and N-demethylation in human liver microsomes and healthy human subjects.

Drug Metab. Lett. 4(1) , 51-5, (2010)

To investigate the effects of black seed on the metabolic activities of CYP3A4 and CYP2D6 in human liver microsomes and in human subjects using dextromethorphan as a probe drug.CYP2D6-mediated O-demet...

更多文献

Morphinan, 3-methoxy

Morphinan, 3-methoxy名称

Morphinan, 3-methoxy物理化学性质

Morphinan, 3-methoxy安全信息

Morphinan, 3-methoxy文献

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