利福霉素钠

利福霉素钠用途

Rifamycin sodium (Rifamycin SV monosodium) 属于安沙霉素抗生素家族,从地中海曲霉或其突变体的发酵中分离出来。Rifamycin sodium 对革兰氏阳性菌和在较小程度上对革兰氏阴性菌具有广泛的抗生素活性。

利福霉素钠名称

[ CAS 号 ]:
14897-39-3

[ 中文名 ]:
利福霉素钠盐

[ 英文名 ]:
Rifamycin sodium

[中文别名 ]:

利福霉素钠

[英文别名 ]:

Rifamycin SV sodium salt
EINECS 238-965-7
Rifamycin SV Monosodium
MFCD00056847
Rifampicin SV sodium
Rifamycin SV hexahydrate sodium salt
Rifamycin sodium
RIFAMYCIN SV SODIUM SALT HEXAHYDRATE
RifaMycin SV MonosodiuM salt
RIFAMYCIN SV-SODIUM

利福霉素钠生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. Floss HG, et al. Rifamycin-mode of action, resistance, and biosynthesis. Chem Rev. 2005 Feb;105(2):621-32.

利福霉素钠物理化学性质

[ 密度 ]:
1.35g/cm3

[ 沸点 ]:
862.1ºC at 760mmHg

[ 熔点 ]:
>215°C (dec.)

[ 分子式 ]:
C₃₇H₄₆NNaO₁₂

[ 分子量 ]:
719.750

[ 闪点 ]:
475.2ºC

[ 精确质量 ]:
719.291748

[ PSA ]:
204.14000

[ LogP ]:
5.18780

[ 外观性状 ]:
粉末

[ 储存条件 ]:
-20°C Freezer

[ 水溶解性 ]:
ethanol: soluble50mg/mL | Soluble in water, alcohol and dimethyl sulfoxide.

利福霉素钠安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
F

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
KD1922500

[ 海关编码 ]:
2941903000

利福霉素钠制备

由发酵获得的利福霉素S钠，用维素C还原，再经分离操作得到该品。

利福霉素钠海关

[ 海关编码 ]: 2941903000

利福霉素钠文献

Polyketide construction via hydrohydroxyalkylation and related alcohol C-H functionalizations: reinventing the chemistry of carbonyl addition.

Nat. Prod. Rep. 31(4) , 504-13, (2014)

Despite the longstanding importance of polyketide natural products in human medicine, nearly all commercial polyketide-based drugs are prepared through fermentation or semi-synthesis. The paucity of m...

No impact of rifamycin selection on tuberculosis treatment outcome in HIV coinfected patients.

AIDS 27(3) , 481-4, (2013)

Rifabutin has been substituted for rifampicin when treating tuberculosis (TB)/HIV coinfection. However, despite reports of anti-TB treatment failure and acquired rifamycin resistance, long-term clinic...

Differential effects of some antibiotics on paraoxonase enzyme activity on human hepatoma cells (HepG2) in vitro.

J. Enzyme Inhib. Med. Chem. 25(5) , 715-9, (2010)

Serum paraoxonase (aryldialkylphosphatase, EC 3.1.8.1., PON1) is an esterase protein synthesised by the liver and released into the serum, where it is associated with HDL lipoproteins. In this study, ...

更多文献

利福霉素钠

利福霉素钠用途

利福霉素钠名称

利福霉素钠生物活性

利福霉素钠物理化学性质

利福霉素钠安全信息

利福霉素钠制备

利福霉素钠海关

利福霉素钠文献

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