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(RS)-MCPG

(RS)-MCPG用途

(RS)-MCPG是一个非选择性的group I/group II代谢型谷氨酸受体的拮抗剂。

(RS)-MCPG名称

[ CAS 号 ]:
146669-29-6

[ 中文名 ]:
(RS)-MCPG

[ 英文名 ]:
(R,S)-MCPG

[中文别名 ]:

(±)-Α-甲基-(4-羧苯基)甘氨酸

[英文别名 ]:

MFCD00210205
4-(1-amino-1-carboxyethyl)benzoic acid
(±)-MCPG
(+/-)MCPG
(RS)-MCPG

(RS)-MCPG生物活性

[ 描述 ]:

(RS)-MCPG是一个非选择性的group I/group II代谢型谷氨酸受体的拮抗剂。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 谷氨酸受体

研究领域 >> 神经疾病

[相关活性小分子]

(RS)-MCPG物理化学性质

[ 密度 ]:
1.39g/cm3

[ 沸点 ]:
230 °C17 mm Hg(lit.)

[ 熔点 ]:
95-98 °C(lit.)

[ 分子式 ]:
C₁₀H₁₁NO₄

[ 分子量 ]:
209.19900

[ 闪点 ]:
221-223°C/10mm

[ 精确质量 ]:
209.06900

[ PSA ]:
100.62000

[ LogP ]:
1.34360

[ 蒸汽压 ]:
5.44E-08mmHg at 25°C

[ 储存条件 ]:
Store at RT

(RS)-MCPGMSDS

详细MSDS(安全技术说明书)

(RS)-MCPG安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

(RS)-MCPG文献

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Dopamine triggers heterosynaptic plasticity.

J. Neurosci. 33(16) , 6759-65, (2013)

As a classic neuromodulator, dopamine has long been thought to modulate, rather than trigger, synaptic plasticity. In contrast, our present results demonstrate that within the parallel projections of ...

The memory-enhancing effects of hippocampal estrogen receptor activation involve metabotropic glutamate receptor signaling.

J. Neurosci. 33(38) , 15184-94, (2013)

Our laboratory has demonstrated that 17β-estradiol (E2) enhances hippocampal memory consolidation via rapid activation of multiple intracellular signaling cascades, including the ERK/MAPK cascade (Fer...

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