<生产厂家价格>

5-碘-6-氨基-1,2-苯并吡喃酮

5-碘-6-氨基-1,2-苯并吡喃酮名称

[ CAS 号 ]:
137881-27-7

[ 中文名 ]:
5-碘-6-氨基-1,2-苯并吡喃酮

[ 英文名 ]:
INH2BP

[英文别名 ]:

5-Iabp
INH2BP
2H-1-Benzopyran-2-one,6-amino-5-iodo
PARP Inhibitor II,INH2BP
5-Iodo-6-amino-1,2-benzopyrone
MFCD00912555

5-碘-6-氨基-1,2-苯并吡喃酮物理化学性质

[ 密度 ]:
2.029g/cm3

[ 沸点 ]:
437.6ºC at 760mmHg

[ 分子式 ]:
C₉H₆INO₂

[ 分子量 ]:
287.05400

[ 闪点 ]:
218.4ºC

[ 精确质量 ]:
286.94400

[ PSA ]:
56.23000

[ LogP ]:
2.56100

[ 蒸汽压 ]:
7.4E-08mmHg at 25°C

[ 折射率 ]:
1.737

5-碘-6-氨基-1,2-苯并吡喃酮MSDS

详细MSDS(安全技术说明书)

5-碘-6-氨基-1,2-苯并吡喃酮安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

5-碘-6-氨基-1,2-苯并吡喃酮文献

The Protective Effect of INH2BP, a Novel PARP Inhibitor 5-Iodo-6-Amino-1,2-Benzopyrone, Against Hydrogen Peroxide-Induced Apoptosis Through ERK and p38 MAPK in H9c2 Cells.

Pharmacology 96 , 259-70, (2015)

INH2BP (5-iodo-6-amino-1,2-benzopyrone), a poly-ADP ribose polymerase inhibitor, has been shown to possess anti-cancer, anti-viral, and anti-inflammation properties. The aim of this study was to inves...

4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase.

Arthritis. Res. Ther. 10 , R107, (2008)

4-Hydroxynonenal (HNE) is one of the most abundant and reactive aldehydes of lipid peroxidation products and exerts various effects on intracellular and extracellular signalling cascades. We have prev...

Dichloroacetate enhances apoptotic cell death via oxidative damage and attenuates lactate production in metformin-treated breast cancer cells.

Breast Cancer Res. Treat. 147(3) , 539-50, (2014)

The unique metabolism of breast cancer cells provides interest in exploiting this phenomenon therapeutically. Metformin, a promising breast cancer therapeutic, targets complex I of the electron transp...

更多文献