(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐

(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐名称

[ CAS 号 ]:
128223-55-2

[ 中文名 ]:
(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐

[ 英文名 ]:
(2s,3r)-3-amino-2-hydroxy-4-phenylbutyric acid hydrochloride

[中文别名 ]:

[英文别名 ]:

(2S,3R)-AHPA

(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐物理化学性质

[ 沸点 ]:
428.5ºC at 760mmHg

[ 分子式 ]:
C₁₀H₁₄ClNO₃

[ 分子量 ]:
231.67600

[ 闪点 ]:
213ºC

[ 精确质量 ]:
231.06600

[ PSA ]:
83.55000

[ LogP ]:
1.50420

[ 蒸汽压 ]:
4.17E-08mmHg at 25°C

[ 储存条件 ]:
−20°C

(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26/36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐合成路线

详细合成路线

(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐上下游产品

(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐上游产品

(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐下游产品

(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐文献

Bestatin analogue from Streptomyces neyagawaensis SL-387.

Biosci. Biotechnol. Biochem. 60 , 898-900, (1996)

A bestatin analogue, (2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl-L-valine (AHPA-Val), from the culture filtrate of Streptomyces neyagawaensis SL-387 was obtained in a chemically defined medium containi...

2S,3R 3-amino-2-hydroxy-4-phenylbutanoic acid derivatives, enkephalinase inhibitors, augment met5-enkephalin-induced antinociception.

Jpn. J. Pharmacol. 46 , 205-210, (1988)

It has been accepted that the periaqueductal gray matter of the mid brain (PAG) and the reticular formation of the medulla oblongata in the brain stem have antinociceptive roles in the pain control pa...

Relationship between enhancement of morphine analgesia and inhibition of enkephalinase by 2S, 3R 3-amino-2-hydroxy-4-phenylbutanoic acid derivatives.

Life Sci. 30 , 1739-1746, (1982)

The effects of nineteen AHPA* derivatives were examined on morphine analgesia by tail-flick test in rats and on enkephalinase inhibition which was based on the formation of tyrosyl-glycyl-glycine from...

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