四氯乙烯_MSDS_用途_密度_四氯乙烯CAS号【127-18-4】

【用途一】
用作有机溶剂、干洗剂、油脂萃取剂、烟幕剂、脱硫剂及织物整理剂等
【用途二】
四氯乙烯用途广泛，主要用作有机溶剂、干洗剂、金属脱脂溶剂，也用作驱肠虫药。四氯乙烯可用作脂肪类萃取剂、灭火剂和烟幕剂等，还可用于合成三氯乙烯和含氟有机化合物等。
【用途三】
广泛用于服装、毛皮、织物的干洗，金属脱脂及油脂抽提等方面，是重要的有机合成原料，有机分析中用作脂肪或脂肪类似物质的溶剂，有机合成。用于ICP-AES、AAS、AFS、ICP-MS、离子色谱等。滴定分析用标准溶液。
【用途四】
有机分析中用作脂肪或脂肪类似物质的溶剂。高压液相色谱试剂。分光光度测定用溶剂。有机合成

[ 密度 ]:
1.7±0.1 g/cm3

[ 沸点 ]:
119.1±30.0 °C at 760 mmHg

[ 熔点 ]:
-22 °C

[ 分子式 ]:
C₂Cl₄

[ 分子量 ]:
165.833

[ 闪点 ]:
27.4±21.9 °C

[ 精确质量 ]:
163.875412

[ LogP ]:
2.95

[ 外观性状 ]:
无色液体带有像醚的气味

[ 蒸汽密度 ]:
5.83 (vs air)

[ 蒸汽压 ]:
19.3±0.2 mmHg at 25°C

[ 折射率 ]:
1.519

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、食品添加剂分开存放,存放需加稳定剂,如对苯二酚

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents, alkali metals, aluminium, strong bases.

[ 凝固点 ]:
-22.0℃

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KX3850000

CHEMICAL NAME :: Ethylene, tetrachloro-

CAS REGISTRY NUMBER :: 127-18-4

BEILSTEIN REFERENCE NO. :: 1361721

LAST UPDATED :: 199806

DATA ITEMS CITED :: 114

MOLECULAR FORMULA :: C2-Cl4

MOLECULAR WEIGHT :: 165.82

WISWESSER LINE NOTATION :: GYGUYGG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human

DOSE/DURATION :: 96 ppm/7H

TOXIC EFFECTS :: Peripheral Nerve and Sensation - local anesthetic Sense Organs and Special Senses (Eye) - conjunctive irritation Behavioral - hallucinations, distorted perceptions

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - child

DOSE/DURATION :: 545 mg/kg

TOXIC EFFECTS :: Behavioral - coma

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 600 ppm/10M

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - conjunctive irritation Behavioral - general anesthetic

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2629 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 34200 mg/m3/8H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4678 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intratracheal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8100 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5200 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 65 gm/kg

TOXIC EFFECTS :: Behavioral - sleep Behavioral - ataxia

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Behavioral - sleep Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 2100 mg/kg

TOXIC EFFECTS :: Liver - liver function tests impaired

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 85 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Behavioral - sleep Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Behavioral - sleep Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >3228 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14 gm/kg/4W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 36 gm/kg/90D-C

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 gm/kg/6W-I

TOXIC EFFECTS :: Liver - other changes Liver - changes in liver weight Biochemical - Metabolism (Intermediary) - lipids including transport

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1750 ppm/6H/14D-I

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 19300 mg/m3/24H/94D-C

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 ppm/4W-C

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7000 ppm/8H/50D-I

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), diffuse Kidney, Ureter, Bladder - changes in blood vessels or in circulation of kidney Blood - changes in spleen

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 49750 ug/kg/3D-I

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Liver - other changes

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 ppm/4H/8W-I

TOXIC EFFECTS :: Liver - fatty liver degeneration

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1750 ppm/6H/14D-I

TOXIC EFFECTS :: Liver - fatty liver degeneration

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 ppm/6H/13W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - other changes Related to Chronic Data - death

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2500 ppm/7H/39D-I

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 200 ppm/7H/32W-I

TOXIC EFFECTS :: Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - gerbil

DOSE/DURATION :: 120 ppm/24H/1Y-C

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Biochemical - Metabolism (Intermediary) - lipids including transport

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 ppm/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Blood - leukemia Reproductive - Tumorigenic effects - testicular tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 195 gm/kg/50W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 ppm/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 240 gm/kg/62W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 ppm/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Blood - leukemia

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 ppm/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 1000 ppm/24H

SEX/DURATION :: female 14 day(s) pre-mating female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 1000 ppm/24H

SEX/DURATION :: female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 900 ppm/7H

SEX/DURATION :: female 7-13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - live birth index (measured after birth) Reproductive - Effects on Newborn - biochemical and metabolic Reproductive - Effects on Newborn - behavioral

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 300 ppm/7H

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 300 ppm/7H

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - homeostasis

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 500 ppm/7H

SEX/DURATION :: male 5 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: DNA damage

TYPE OF TEST :: Mutation test systems - not otherwise specified

TYPE OF TEST :: Sperm Morphology

MUTATION DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TEST SYSTEM :: Rodent - hamster Lung

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,135,1987 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-STEL 685 mg/m3 (100 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 170 mg/m3 (25 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Sufficient Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,355,1987 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 63,159,1995 IARC Cancer Review:Human Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 63,159,1995 IARC Cancer Review:Human Inadequate Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,355,1987 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,355,1987 IARC Cancer Review:Group 2A IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 63,159,1995 TOXICOLOGY REVIEW CMSHAF Chemosphere. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1972- Volume(issue)/page/year: 6,517,1977 TOXICOLOGY REVIEW AJMEAZ American Journal of Medicine. (Technical Pub., 875 Third Ave., New York, NY 10022) V.1- 1946- Volume(issue)/page/year: 38,409,1965 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD-air:TWA 100 ppm (670 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,201,1971 OSHA PEL (Gen Indu):8H TWA 100 ppm;CL 200;Pk 300/5M/3H CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 100 ppm (670 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 100 ppm (670 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 100 ppm (670 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 5 ppm (35 mg/m3);Skin JAN 1993 OEL-AUSTRALIA:TWA 50 ppm (335 mg/m3);STEL 150 ppm;Carcinogen JAN 1993 OEL-BELGIUM:TWA 50 ppm (339 mg/m3);STEL 200 ppm (1368 mg/m3) JAN 1993 OEL-DENMARK:TWA 30 ppm (200 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 50 ppm (335 mg/m3);STEL 75 ppm (520 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 50 ppm (335 mg/m3) JAN 1993 OEL-GERMANY:TWA 50 ppm (345 mg/m3);Carcinogen JAN 1993 OEL-HUNGARY:STEL 50 mg/m3;Skin;Carcinogen JAN 1993 OEL-JAPAN:TWA 50 ppm (340 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 35 ppm (240 mg/m3);Skin JAN 1993 OEL-THE PHILIPPINES:TWA 100 ppm (670 mg/m3) JAN 1993 OEL-POLAND:TWA 60 mg/m3 JAN 1993 OEL-RUSSIA:TWA 50 ppm;STEL 10 mg/m3 JAN 1993 OEL-SWEDEN:TWA 10 ppm (70 mg/m3);STEL 25 ppm (170 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 50 ppm (345 mg/m3);STEL 100 ppm;Skin JAN 1993 OEL-THAILAND:TWA 100 ppm;STEL 200 ppm JAN 1993 OEL-UNITED KINGDOM:TWA 50 ppm (335 mg/m3);STEL 150 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO TETRACHLOROETHYLENE-air:CA lowest feasible conc. REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 54790 No. of Facilities: 52013 (estimated) No. of Industries: 288 No. of Occupations: 155 No. of Employees: 549154 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 54790 No. of Facilities: 49025 (estimated) No. of Industries: 268 No. of Occupations: 151 No. of Employees: 688110 (estimated) No. of Female Employees: 177342 (estimated)

[ 符号 ]:

GHS07, GHS08, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H317-H319-H336-H351-H411

[ 警示性声明 ]:
P273-P280-P304 + P340 + P312-P333 + P313-P337 + P313-P391

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R40;R51/53

[ 安全声明 (欧洲) ]:
S23-S36/37-S61-S45-S24-S16-S7

[ 危险品运输编码 ]:
UN 1897 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
KX3850000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2903230000

详细合成路线

四氯乙烯上游产品

四氯乙烯下游产品

1.乙烯法本法可联产三氯乙烯和四氯乙烯，分下列二法。a）直接氯化乙烯和氯在含FeCl3催化剂的1,2-二氯乙烷溶液中，于280-450℃进行反应，生成1,2-二氯乙烷，再进一步氯化成三氯乙烯和四氯乙烯，经蒸馏后，分别用NH3中和、洗涤、干燥，即得成品。b）氧氯化法以乙烯和氯加成生成1,2-二氯乙烷，1,2-二氯乙烷与氯、氧在以CuCl2和KCl为催化剂以及425℃、138-207kPa条件下进行氧氯化反应，产物经冷却、水洗、干燥后蒸馏，得高纯度产品。

2.烃类氧化法将含甲烷、乙烷、丙烷、丙烯等的烃类混合物于50-500℃氯化热解，得氯代烃类的混合物，精馏后分离成各种产品。

3.乙炔法乙炔和氯加热氯化生成1,1,2,2-四氯乙烷，用碱脱去氯化氢得三氯乙烯，再经氯化生成五氯乙烷，然后再用碱脱去氯化氢得四氯乙烯。因乙炔价昂，已逐步为乙烯法等代替。

4.制法乙炔氯化后生成四氯乙烷，经碱解脱去HCl后成为三氯乙烯，再氯化则成为五氯乙烷，然后用氢氧化钙脱去HCl后即成为四氯乙烯。

为制备色谱纯四氯乙烯，可以氮气为载气，在装有SE30/白色硅藻土担体固定相柱的制备气相色谱仪上注入其粗品，经分离收集其主峰组分，然后装入玻璃安瓿瓶密封即可。

5.由五氯乙烷与石灰乳作用后脱氢而得。

[ 海关编码 ]: 2903230000

[ 中文概述 ]:
2903230000 四氯乙烯。监管条件:X(有毒化学品环境管理放行通知单)。增值税率:17.0%。退税率:9.0%。最低关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 原产地证据文件及编号(例附原产地证书, 原产于欧盟、美国的

[ 监管条件 ]: X.有毒化学品环境管理放行通知单

[ Summary ]:
2903230000 perchloroethene。supervision conditions:x(environment control release notice for poisonous chemicals)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:5.5%。general tariff:30.0%

A method for quantification of volatile organic compounds in blood by SPME-GC-MS/MS with broader application: From non-occupational exposure population to exposure studies.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 992 , 76-85, (2015)

Humans are continuously exposed to volatile organic compounds (VOCs) as these chemicals are ubiquitously present in most indoor and outdoor environments. In order to assess recent exposure to VOCs for...

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

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Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental...

QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES.

Eur. J. Med. Chem. 43 , 714-40, (2008)

Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org...

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公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥88.0/500ml

联系人：刘佳

产品详情：四氯乙烯

公司名：盘锦研峰科技有限公司

区域：盘锦市盘锦市双台子区

价格：
￥90.0/100ton

联系人：王迎

产品详情：四氯乙烯

公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥需询单/1mg ￥需询单/1g ￥需询单/1g ￥需询单/1g

联系人：阿拉丁李高志

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公司名：济南创世化工有限公司

区域：济南市天桥区

价格：
￥需询单/300kg

联系人：严玲玲

产品详情：四氯乙烯

公司名：济南世纪通达化工有限公司

区域：济南市天桥区

价格：
￥3900.0/300kg ￥12500.0/1ton

联系人：王经理

产品详情：四氯乙烯

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