海葱苷

海葱苷名称

[ CAS 号 ]:
124-99-2

[ 中文名 ]:
海葱苷

[ 英文名 ]:
Bufa-4,20,22-trienolide,3-[(6-deoxy-4-O-b-D-glucopyranosyl-a-L-mannopyranosyl)oxy]-14-hydroxy-,(3b)-

[英文别名 ]:

Transvalin
Transvaalin
EINECS 204-721-3
Scillaren

海葱苷物理化学性质

[ 密度 ]:
1.44g/cm3

[ 沸点 ]:
889.8ºC at 760mmHg

[ 分子式 ]:
C₃₆H₅₂O₁₃

[ 分子量 ]:
692.79000

[ 闪点 ]:
276.1ºC

[ 精确质量 ]:
692.34100

[ PSA ]:
208.74000

[ LogP ]:
0.83800

[ 蒸汽压 ]:
0mmHg at 25°C

[ 折射率 ]:
1.639

海葱苷MSDS

详细MSDS(安全技术说明书)

海葱苷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EI3325000

CHEMICAL NAME :: Bufa-4,20,22-trienolide, 3-beta-((6-deoxy-4-O-beta-D-glucopyranosyl-alpha-L-ma nnopyranosyl) oxy)-14-hydroxy-

CAS REGISTRY NUMBER :: 124-99-2

BEILSTEIN REFERENCE NO. :: 0076216

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C36-H52-O13

MOLECULAR WEIGHT :: 692.88

WISWESSER LINE NOTATION :: L E5 B666 MUTJ A1 E1 IQ F- ET6OVJ& OO- CT6OTJ B1Q DQ EQ FO- CT6OTJ B1 DQ EQ FQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15500 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,848,1961

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 5200 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FARMA8 Farmacognosia. (Madrid, Spain) V.1-27, 1942-62. Discontinued. Volume(issue)/page/year: 13,375,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 167 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 111,365,1954

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 146 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year: -,72,1963

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 353 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 252,314,1966 *** REVIEWS *** TOXICOLOGY REVIEW 85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year: -,193,1963

海葱苷安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301

[ 警示性声明 ]:
P301 + P310

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII

海葱苷文献

[Densitometric determination of proscillaridin A, scillaren A and scilliroside].

Il Farmaco 35(1) , 32-46, (1980)

更多文献

海葱苷