<生产厂家价格>

邻羧基苯甲醛

邻羧基苯甲醛用途

2-羧基苯甲醛是一种化合物。2-羧基苯甲醛由苯环组成,醛和羧酸作为相互邻接的取代基。2-羧基苯甲醛可用于与金属离子形成配体。2-羧基苯甲醛缩氨基硫脲的Ni(II)和Cu(II)配合物具有抗癌和抗菌活性[1]。

邻羧基苯甲醛名称

[ CAS 号 ]:
119-67-5

[ 中文名 ]:
邻羧基苯甲醛

[ 英文名 ]:
2-Carboxybenzaldehyde

[中文别名 ]:

[英文别名 ]:

Phthalaldehydic Acid
Benzoic acid, 2-formyl-
EINECS 204-342-3
Benzaldehyde-2-carboxylic Acid
2-carboxybenzaldehyde
2-Formylbenzoic acid
MFCD00003336
2-Formyl-benzoic acid

邻羧基苯甲醛生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

研究领域 >> 感染

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Chandra S, et al. Synthesis, spectroscopic, anticancer and antibacterial studies of Ni(II) and Cu(II) complexes with 2-carboxybenzaldehyde thiosemicarbazone. Spectrochim Acta A Mol Biomol Spectrosc. 2014;129:333-338.

邻羧基苯甲醛物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
321.8±25.0 °C at 760 mmHg

[ 熔点 ]:
94-96 °C(lit.)

[ 分子式 ]:
C₈H₆O₃

[ 分子量 ]:
150.13

[ 闪点 ]:
162.6±19.7 °C

[ 精确质量 ]:
150.031693

[ PSA ]:
54.37000

[ LogP ]:
0.77

[ 外观性状 ]:
白色晶体粉末

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.620

[ 储存条件 ]:
室温，密封

[ 水溶解性 ]:
soluble

邻羧基苯甲醛MSDS

邻羧基苯甲醛毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TH7015000

CHEMICAL NAME :: Phthalaldehydic acid

CAS REGISTRY NUMBER :: 119-67-5

BEILSTEIN REFERENCE NO. :: 0742381

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C8-H6-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,665,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2430 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,665,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4480 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,665,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1860 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,665,1974

邻羧基苯甲醛安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S24/25

[ 危险品运输编码 ]:
PG2

[ WGK德国 ]:
2

[ RTECS号 ]:
TH7015000

[ 海关编码 ]:
29183000

邻羧基苯甲醛合成路线

邻羧基苯甲醛上下游产品

邻羧基苯甲醛上游产品

邻羧基苯甲醛下游产品

邻羧基苯甲醛制备

由苯酚经溴化、水解而得。将苯酞加热到140-145℃，通溴反应，控制通入速度，使反应尾气基本上无溴蒸气排出。通溴毕，在120℃通二氧化碳与减压将残留的溴化氢除出。反应物加水，在沸腾水浴内水解0.5h。冷却，析出邻羧基苯甲醛。收率60%。

邻羧基苯甲醛海关

[ 海关编码 ]: 2918300090

[ 中文概述 ]:
2918300090 其他含醛基或酮基不含其他含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

邻羧基苯甲醛文献

Highly efficient synthesis of N-substituted isoindolinones and phthalazinones using Pt nanowires as catalysts.

Org. Lett. 14(7) , 1876-9, (2012)

A series of N-substituted isoindolinones have been successfully synthesized through the reductive C-N coupling and intramolecular amidation of 2-carboxybenzaldehyde and amines. This one-pot synthesis ...

Degradation of fluoranthene by Pasteurella sp. IFA and Mycobacterium sp. PYR-1:isolation and identification of metabolites.

J. Appl. Microbiol. 85(4) , 746-54, (1998)

The findings from a biodegradability study of fluoranthene using two pure bacterial strains, Pasteurella sp. IFA (B-2) and Mycobacterium sp. PYR-1 (AM) are reported. Of total fluoranthene, 24% (B-2) a...

Degradation of phenanthrene by the rhizobacterium Ensifer meliloti.

Biodegradation 25(6) , 787-95, (2014)

The biodegradation of the polycyclic aromatic hydrocarbon phenantherene by the rhizobacterial strain Ensifer meliloti P221, isolated from the root zone of plant grown in PAH-contaminated soil was stud...

更多文献